Evidence map›Paper›PMID 39924540›Full record

ArticleSignal transduction and targeted therapy2025

Uveal melanoma with a GNA11/GNAQ mutation secretes VEGF for systemic spread.

Nguyễn Thị Thanh Nhàn, Sanjay Ganesh, Daniel E Maidana, Michael J Heiferman, Kaori H Yamada

Abstract readLetter
In one paragraph

Article in Signal transduction and targeted therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nguyễn Thị Thanh NhànDepartment of Pharmacology & Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0002-9426-8483
Sanjay GaneshDepartment of Pharmacology & Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612, USA.ORCID http://orcid.org/0009-0006-9694-594X
Daniel E MaidanaDepartment of Ophthalmology & Visual Sciences, University of Illinois College of Medicine, Chicago, IL, 60612, USA.
Michael J HeifermanDepartment of Ophthalmology & Visual Sciences, University of Illinois College of Medicine, Chicago, IL, 60612, USA.ORCID http://orcid.org/0000-0003-3456-0164
Kaori H YamadaDepartment of Pharmacology & Regenerative Medicine, University of Illinois College of Medicine, Chicago, IL, 60612, USA. horiguch@uic.edu.ORCID http://orcid.org/0000-0003-4075-9866

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI MCANANY, JAMES JASON · 1985 to 2025
$14.8M
UIC K12 Independent Clinical Vision Scientist Development ProgramK12EY021475 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI ALI R DJALILIAN, CHARLOTTE E JOSLIN · 2011 to 2026
$6.7M
Role of VEGFR2 trafficking in pathological angiogenesis in age related macular degenerationR01EY029339 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI YAMADA, KAORI HORIGUCHI · 2019 to 2023
$2.0M
Defining the Role of Retinal Microglia and Infiltrating Monocytes on Photoreceptor Cell Death in Retinal DetachmentK08EY034935 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Daniel Enrique E. Maidana · 2023 to 2026
$850k
American Cancer Society (American Cancer Society, Inc.) AHEAD-DBG-23-1156429-01-MMNEI NIH HHS K08 EY034935NEI NIH HHS K12 EY021475NEI NIH HHS P30 EY001792NEI NIH HHS R01 EY029339U.S. Department of Health & Human Services | National Institutes of Health (NIH) K08EY034935U.S. Department of Health & Human Services | National Institutes of Health (NIH) K12EY021475U.S. Department of Health & Human Services | National Institutes of Health (NIH) P30EY001792U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01EY029339
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID39924540
PMCPMC11808083

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.