Evidence map›Paper›PMID 39924474›Full record

ArticleOne health outlook2025

Documenting challenges in achieving rabies elimination by 2030 in low-middle income countries; a Kenyan case study from Lamu County, 2020-2022: mixed methods approach.

Nassoro Mwanyalu, Athman Mwatondo, Veronicah Chuchu, Kimani Maina, Mathew Muturi, Mathew Mutiiria, Daniel Chepkwony, Maurice Owiny, Peninah Munyua

Abstract read
In one paragraph

Article in One health outlook, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nassoro MwanyaluKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya. namwanyalu@gmail.com.ORCID http://orcid.org/0000-0003-4937-5754
Athman MwatondoKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Veronicah ChuchuKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Kimani MainaKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Mathew MuturiKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Mathew MutiiriaKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Daniel ChepkwonyKenya Zoonotic Diseases Unit, Ministry of Health, Nairobi, Kenya.
Maurice OwinyField Epidemiology and Laboratory Training Program, Ministry of Health, Nairobi, Kenya.
Peninah MunyuaDivision of Global Health Protection, United States Centers for Disease Control and Prevention, Nairobi, Kenya.

Funding

Zoonotic and Emerging Infectious Diseases Training ProgramD43TW011519 · FIC · WASHINGTON STATE UNIVERSITY · PI Walter Godfrey Jaoko, Thumbi Mwangi · 2020 to 2026
$1.2M
FIC NIH HHS D43 TW011519This outbreak investigation was supported through U.S. Centers for Disease Control and Prevention, Global Health Security funding cooperative agreement with the Kenya Ministry of Health CoAg # GH15-162702CONT16
6 · The paper itself

Abstract

backgroundKenya launched a Rabies Elimination Strategy in 2014, aiming to end human rabies deaths by 2030. In March 2022, Lamu County reported increased cases of human dog bites and suspected rabies deaths to the Ministry of Health (MoH). We aimed to establish the extent of the rabies outbreak in humans and animals and determine the challenges to achieving rabies elimination by 2030.

methodsWe extracted dog bite reports from the Kenya Health Information System (KHIS), national surveillance database system, and reviewed medical records at health facilities in Lamu County for suspected human rabies deaths from 2020 to 2022. We obtained information about animal bites and illnesses in deceased persons, checked the availability of anti-rabies vaccines in health facilities, and administered rabies knowledge and practice questionnaires to health workers. For categorical data, frequencies and proportions were determined.

resultsThere were 787 dog bite cases and six human rabies cases. Only a third (2/6) of the rabies cases were uploaded to the KHIS. The county used targeted dog vaccination, and samples were not collected from the biting dogs. Regarding the availability of human rabies vaccines, half (8/16) of the facilities had the human rabies vaccine, and 19% (3/16) had both the human rabies vaccine and rabies immunoglobulin (RIG). Rabies vaccine stock-outs were common at 73% (11/16). Only 25% (18/73) of the health workers reported their first action would be to clean the bite wound with running water and soap for 15 min. Additionally, 86% (54/63) did not know the recommended human rabies vaccine and RIG dosage and schedule, while 25% (18/73) of healthcare workers were satisfied with the existing information-sharing mechanisms between veterinary and human health departments for rabies prevention and control.

conclusionsThere was underreporting of rabies cases, a lack of awareness of bite wound management at health facilities, and persistent stockouts of human rabies vaccines. We suggest training healthcare workers on animal bite case management and improving One Health information exchange.

Indexed as

KenyaOne healthPost-exposure prophylaxisRabies eliminationRabies immunoglobulinZero rabies cases

Identifiers

PMID39924474
PMCPMC11809077

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.