Evidence map›Paper›PMID 39924244›Full record

ReviewInternal medicine (Tokyo, Japan)2025

Waldenström's Macroglobulinemia/Lymphoplasmacytic Lymphoma Developing Renal AA Amyloidosis: A Case Report and Literature Review.

Yusuke Ishizuka, Yuji Oe, Sosuke Kinomura, Saori Kin, Yuji Noguchi, Koichi Kikuchi, Mai Yoshida, Rui Makino, Koji Okamoto, Tasuku Nagasawa and 6 more

Erratum issuedAbstract readCase ReportsReview
In one paragraph

Review in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors.

Yusuke IshizukaDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Yuji OeDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Sosuke KinomuraDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Saori KinDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Yuji NoguchiDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Koichi KikuchiDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Mai YoshidaDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Rui MakinoDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Koji OkamotoDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Tasuku NagasawaDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Takafumi ToyoharaDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Mariko MiyazakiDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Hiroshi SatoDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.
Yasushi OnishiDepartment of Hematology, Tohoku University Graduate School of Medicine, Japan.
Hitoshi WaritaDepartment of Neurology, Tohoku University Graduate School of Medicine, Japan.
Tetsuhiro TanakaDepartment of Nephrology, Tohoku University Graduate School of Medicine, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AA amyloidosis is a rare renal complication of Waldenström's macroglobulinemia/lymphoplasmacytic lymphoma (WM/LPL). A 66-year-old man with WM/LPL presented with nephrotic syndrome. A renal biopsy showed AA amyloidosis. Chemotherapy resulted in the remission of hematologic and nephrotic syndromes. Two years into follow-up, he became infected with coronavirus disease 2019 and had massive proteinuria, despite no relapse of WM/LPL. A second renal biopsy confirmed a diagnosis of AA amyloidosis. However, increased prednisolone did not improve proteinuria. The patient ultimately died of cryptococcal meningitis. This case highlights the diverse spectrum of renal involvement in monoclonal IgM-secreting diseases and difficulty in managing fatal complications.

Indexed as

AmyloidosisKidney DiseasesWaldenstrom MacroglobulinemiaAgedCOVID-19Fatal OutcomeHumansKidneyMaleNephrotic SyndromeSerum Amyloid A ProteinSerum Amyloid A ProteinCOVID-19monoclonal IgM-secreting diseasenephrotic syndromeprednisolone

Identifiers

PMID39924244
PMCPMC12097815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.