ArticleInternal medicine (Tokyo, Japan)2025
Unexpected Hypotension in a Female Patient with Fabry Disease: Switching from Agalsidase α to β after Long-term ERT.
Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Reply to Dr. Finsterer's Letter on 'Unexpected Hypotension in a Female Patient with Fabry Disease'.Internal medicine (Tokyo, Japan) · 2026Article
- Agalsidase-A for Fabry's Disease Can Be Made Responsible for Hypotension Only after Sufficient Exclusion of Alternative Causes.Internal medicine (Tokyo, Japan) · 2026Article
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14 authors.
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Abstract
Fabry disease is a rare X-linked lysosomal storage disorder. Enzyme replacement therapies (ERTs), such as agalsidase α and β, are available treatment options. While infusion-related reactions (IRRs) are known to occur at the initiation of ERT owing to immune responses, there is limited information on IRRs during long-term ERT. We report the case of a female patient with Fabry disease who developed unexpected hypotension after six years of stable treatment with agalsidase α, leading to a switch to agalsidase β. Continuous monitoring may be essential to identify potential IRRs in female patients with Fabry disease receiving long-term ERT.
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