Trial reportDrug and alcohol dependence2025
A randomized pilot trial of two forms of behavioral economics intervention to improve engagement in buprenorphine-naloxone treatment among patients with opioid use disorder.
Trial report in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- A behavioral economics substance-free activity session (SFAS) approach to reducing substance use: Narrative review and intervention manual.Experimental and clinical psychopharmacology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundBuprenorphine-naloxone treatment engagement for those with opioid use disorder (OUD) is very low. The current randomized effectiveness trial piloted two psychosocial interventions developed to increase buprenorphine-naloxone treatment engagement in 44 individuals with opioid use disorder (OUD) recruited from an OUD treatment clinic.
methodsParticipants were randomized to receive either variable-value contingency management (CM) or a brief substance free activities session plus mindfulness (BSM) cognitive-behavioral intervention at each of the first 4 return visits to the provider. The primary outcome was buprenorphine metabolite in urine and attendance at 2 or more of 4 possible physician visits.
resultsRelatively high treatment engagement was observed over 16 weeks with no significant differences in effectiveness between the two intervention arms (p = 0.526). There was slightly better treatment engagement in the CM arm (73 % vs. 59 % engaged in CM and BSM arm, respectively), but this was not statistically significant with n = 22 participants in each group. Treatment engagement was significantly better for those who presented at the clinic with prior buprenorphine exposure: 19 (86 %) of the 22 participants with buprenorphine present in urine at baseline were engaged, whereas only 9 (43 %) out of 21 participants without buprenorphine present in urine at baseline were subsequently engaged (p = 0.004).
conclusionsResults suggested that patients who are not taking buprenorphine at the start of a psychosocial intervention may require more intensive treatment engagementinterventions than those already taking medication. Satisfaction data were similarly high across the interventions, and qualitative items identified helpful intervention components.
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Registered trials
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