Evidence map›Paper›PMID 39923071›Full record

ArticleBMC oral health2025

Necessity of applying anatomical unit resection surgery in suspected posterior oral squamous cell carcinoma.

Bowen Dai, Hongyu Tan, Zhimin Yang, Zhaojian Gong, Kun Wu, Hanjiang Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bowen DaiDepartment of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University, Renmin road, No. 139, Changsha, Hunan, 410011, China.
Hongyu TanDepartment of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University, Renmin road, No. 139, Changsha, Hunan, 410011, China.
Zhimin YangDepartment of Oral and Maxillofacial Surgery, Xiangya Hospital of Central South University, Changsha, China.
Zhaojian GongDepartment of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University, Renmin road, No. 139, Changsha, Hunan, 410011, China. gongzhaojian4458@csu.edu.cn.
Kun WuDepartment of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University, Renmin road, No. 139, Changsha, Hunan, 410011, China. wukun1302@csu.edu.cn.
Hanjiang WuDepartment of Oral and Maxillofacial Surgery, Second Xiangya Hospital of Central South University, Renmin road, No. 139, Changsha, Hunan, 410011, China. wuhanjiang@csu.edu.cn.

Funding

China Postdoctoral Science Foundation 2023M732285
6 · The paper itself

Abstract

objectiveAnatomic unit resection surgery (AURS), previously introduced, significantly improves the prognosis of oral cell squamous carcinoma (OSCC) patients with posterior oral anatomical complex (POAC) involvement. This study aims to evaluate the necessity of AURS in patients with OSCC suspected to involve the POAC.

methodsWe conducted a retrospective study of 127 patients diagnosed OSCC with identical POAC involvement or suspected POAC involvement. Patients were classified based on the extent of POAC involvement determined from preoperative imaging. Kaplan-Meier analysis was performed to identify the impact of surgery approaches on the prognosis of patients. Univariable and multivariable cox analysis were conducted to identify independent prognostic factors of the patients.

resultsIn total, 65 patients with suspected POAC involvement, 24 cases underwent AURS while 41 underwent conventional surgery. 62 patients with identical POAC involvement, 31 cases underwent AURS while 31 underwent conventional surgery. The AURS group demonstrated significantly superior disease-free survival (DFS) rates (75.0% vs. 43.9%) and local-regional control rates (79.2% vs. 48.8%) for suspected POAC involvement. For identical POAC involvement, AURS also resulted in better DFS (51.6% vs. 19.4%) and local-regional control (64.5% vs. 25.8%). Surgery protocol, tumor involvement level, lymphatic invasion and pN staging were identified as independent prognostic factors for both DFS and local-regional control.

conclusionsAURS is a necessary surgical approach for both suspected and identical POAC involvement in OSCC patients, significantly improving prognosis and local-regional control rate.

Indexed as

Carcinoma, Squamous CellMouth NeoplasmsAdultAgedAged, 80 and overDisease-Free SurvivalFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesDisease-free survivalLocal neoplasm recurrenceMasticator spaceSkull base neoplasm

Identifiers

PMID39923071
PMCPMC11807295

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.