Evidence map›Paper›PMID 39922987›Full record

ArticleDermatology and therapy2025

Healthcare Resource Utilization and Economic Burden of Prurigo Nodularis in the United States.

Shawn G Kwatra, Ashis K Das, Eunice Chang, Caleb Paydar, Donia Bahloul, Chao Chen, Ryan B Thomas

Abstract read
In one paragraph

Article in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shawn G KwatraDepartment of Dermatology, University of Maryland School of Medicine, Baltimore, MD, USA.
Ashis K DasPHAR (Partnership for Health Analytic Research), Beverly Hills, CA, USA.
Eunice ChangPHAR (Partnership for Health Analytic Research), Beverly Hills, CA, USA.
Caleb PaydarPHAR (Partnership for Health Analytic Research), Beverly Hills, CA, USA.
Donia BahloulSanofi, Gentilly, France.
Chao ChenRegeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA.
Ryan B ThomasRegeneron Pharmaceuticals Inc, 777 Old Saw Mill River Road, Tarrytown, NY, 10591, USA. ryan.thomas@regeneron.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe impacts of prurigo nodularis (PN) on healthcare resource utilization (HCRU) and associated costs are unclear.

methodsThis retrospective, cross-sectional claims analysis (IQVIA PharMetrics

resultsWe matched 16,888 patients with PN with 16,888 controls. Most comorbidities (mental health, metabolic conditions, type 2 inflammatory diseases) appeared more frequently in patients with PN versus controls. HCRU was significantly (P < 0.001) higher for patients with PN versus controls, including mean (standard deviation, SD) number of outpatient visits (17.0 [15.5] vs 8.1 [10.7]) and proportion of patients with hospitalizations (9.3% vs 5.9%). Mean (SD) total costs were significantly (P < 0.001) greater for patients with PN versus controls ($18,315 [$66,476] vs $8451 [$30,982]).

conclusionsPatients with PN receiving advanced therapy had higher HCRU and costs versus localized/no therapy. Patients with PN (particularly those receiving advanced therapies) incurred higher all-cause HCRU burden and associated costs than matched controls. Enhanced feature (slides, video, animation) (MP4 12313 KB).

Indexed as

Claims analysisHealthcare resource utilizationPrurigo nodularis

Identifiers

PMID39922987
PMCPMC11832852

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