Evidence map›Paper›PMID 39922950›Full record

ArticleScientific reports2025

Assessment of serum survivin in women with placenta previa and accreta spectrum: a cross-sectional study.

Nevin Yilmaz, Isil Turan Bakirci, Busra Sahin, Gokhan Bolluk, Esra Can, Huri Dedeakayogullari

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nevin YilmazDepartment of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Health Sciences University, Istanbul, Turkey. drnevinyilmaz@hotmail.com.
Isil Turan BakirciDepartment of Perinatology, Basaksehir Cam and Sakura City Hospital, Health Sciences University, Istanbul, Turkey.
Busra SahinPrivate Ordu Sevgi Hospital, Ordu, Turkey.
Gokhan BollukDepartment of Perinatology, Basaksehir Cam and Sakura City Hospital, Health Sciences University, Istanbul, Turkey.
Esra CanDepartment of Obstetrics and Gynecology, Kanuni Sultan Suleyman Training and Research Hospital, Health Sciences University, Istanbul, Turkey.
Huri DedeakayogullariDepartment of Medical Biochemistry, Faculty of Medicine, Biruni University, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to examine the relationship between maternal serum survivin levels and placental disorders by comparing these levels across cases of normal placentation, placenta previa, and placenta accreta spectrum (PAS). In this prospective cross-sectional study, we enrolled 84 pregnant women categorized into control (n = 42), placenta previa (n = 24), and PAS (n = 28) groups. Serum survivin levels were quantitatively determined using ELISA, and statistical analyses were performed using ANOVA and post-hoc tests. Serum survivin levels were significantly elevated in the placenta previa (348.3 pg/mL, range: 173.0-776.4) and PAS groups (785 pg/mL, range: 324.50-1122) compared to controls (177.9 pg/mL, range: 87.3-242.0) (p < 0.05), suggesting an association between survivin expression and abnormal placental adherence and invasion. Our findings demonstrate significant associations between elevated serum survivin levels and placental disorders, specifically placenta previa and PAS. These associations suggest a potential role for survivin in the pathogenesis of placental complications and warrant further investigation through longitudinal studies.

Indexed as

Placenta AccretaPlacenta PreviaSurvivinAdultBiomarkersCross-Sectional StudiesFemaleHumansPregnancyProspective StudiesYoung AdultBiomarkersBIRC5 protein, humanSurvivinPlacenta accreta spectrumPlacenta previaSurvivin

Identifiers

PMID39922950
PMCPMC11807129

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.