Evidence map›Paper›PMID 39922573›Full record

ArticleBMJ case reports2025

Two cases of highly concentrated hydrogen peroxide poisoning with portal venous gas treated using hyperbaric oxygen therapy.

Marie Vallélian, André Juillerat, Matea Sunic, Claudio Schneider, Sylvain Boet

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Marie Vallélian *Department of Medicine, General Internal Medicine Service, Geneva University Hospitals, Geneva, Switzerland.
André Juillerat *Department of Medicine, General Internal Medicine Service, Geneva University Hospitals, Geneva, Switzerland.
Matea SunicDepartment of Medicine, General Internal Medicine Service, Inselspital University Hospital Bern, Bern, Switzerland.
Claudio SchneiderDepartment of Medicine, General Internal Medicine Service, Geneva University Hospitals, Geneva, Switzerland.
Sylvain BoetDiving and Hyperbaric Unit, Division of Emergency Medicine, Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneve, Switzerland sylvain.boet@unige.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen peroxide poisoning is a rare but potentially severe poisoning that can cause digestive tract irritation and/or gas embolism when ingested. The clinical presentation varies from asymptomatic patients to severe embolic consequences or even death. There is little evidence on the treatment of such poisoning to guide physicians in caring for these patients. This paper reports on two cases of highly concentrated hydrogen peroxide poisoning after accidental ingestion. Both patients showed evidence of portal venous gas, with one patient exhibiting significant symptoms while the other did not. Both were treated with hyperbaric oxygen therapy (HBOT), with a follow-up CT scan revealing a complete resolution of the portal venous gas. This suggests that HBOT is effective for both symptomatic and asymptomatic patients with portal venous gas and should be considered as an effective treatment option in cases of highly concentrated hydrogen peroxide poisoning.

Indexed as

Embolism, AirHydrogen PeroxideHyperbaric OxygenationPortal VeinAdultFemaleHumansMaleMiddle AgedTomography, X-Ray ComputedTreatment OutcomeHydrogen PeroxideGas/Free GasPoisoning

Identifiers

PMID39922573
PMCPMC12034919

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.