The difference in arterial baroreflex sensitivity between the supine and standing positions in healthy subjects.

Teruhiko Sakamoto, Satoshi Mitsuyama, Toru Nagasawa, Kazuomi Kario, Seiji Ozawa

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Article in The journal of physiological sciences : JPS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 authors.

Teruhiko SakamotoDepartment of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaohrui, Takasaki, Gunma 370-0033, Japan.

Satoshi MitsuyamaDepartment of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaohrui, Takasaki, Gunma 370-0033, Japan.

Toru NagasawaDepartment of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaohrui, Takasaki, Gunma 370-0033, Japan.

Kazuomi KarioDivision of Cardiovascular Medicine, Department of Medicine, Jichi Medical University School of Medicine, Shimotsuke, Tochigi 329-0498, Japan.

Seiji OzawaDepartment of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaohrui, Takasaki, Gunma 370-0033, Japan. Electronic address: sozawa@takasaki-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spectral analysis of heart rate variability (HRV) has long been considered a practical, noninvasive tool to assess autonomic nervous functions that regulate the cardiovascular system. The conventional method, however, has limitations in characterizing transient changes of HRV. We have overcome this problem by adopting the time-frequency analysis method. Using this method, we attempted to clarify differences in the arterial baroreflex (ABR) activity during a transient change in the heart rate between the supine and standing positions in healthy subjects. We found that the ABR gain was significantly greater in the supine position compared to standing, and this gain increase was due to transient increases in 0.15 to 0.20 Hz components of HRV spectral powers caused by enhanced cardiac vagal outflow. Based on these findings, we conclude that the orthostatic stress induced by the postural change from supine to standing markedly reduces the baroreflex gain by suppressing high-frequency cardiac vagal outflow.

Indexed as

ArteriesBaroreflexPostureStanding PositionAdultAutonomic Nervous SystemBlood PressureFemaleHealthy VolunteersHeart RateHumansMaleSupine PositionVagus NerveYoung AdultArterial baroreflexBlood pressure fluctuationCoherenceCross-spectral analysisHeart rate variabilityTransfer function gain

Identifiers

PMID39922034

DOI10.1016/j.jphyss.2025.100006

PMCPMC11979646

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.