Evidence map›Paper›PMID 39921423›Full record

ArticleThe American journal on addictions2025

Adverse childhood experiences, insecure attachment, and appointment compliance in an outpatient addiction psychiatry treatment population.

Joanna E Chambers, Susan M Perkins, Kelly M Mosesso, Azziza Ahdoot, Camila L Arnaudo, R Andrew Chambers

Abstract read
In one paragraph

Article in The American journal on addictions, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joanna E ChambersDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Susan M PerkinsBiostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Kelly M MosessoBiostatistics & Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Azziza AhdootMemorial Sloan Kettering Cancer Center, New York, New York, USA.
Camila L ArnaudoDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA.
R Andrew ChambersDepartment of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA.ORCID http://orcid.org/0000-0001-9882-0928

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
AMPA Antagonism: A Novel Pharmacology for Launching Recovery from Opioid AddictionUG3DA050923 · NIDA · INDIANA UNIVERSITY INDIANAPOLIS · PI CHAMBERS, ROBERT ANDREW, TOOMBS, CHRISTOPHER FRANCIS · 2020 to 2020
$1.9M
HRSA HHS T25HP37617NCI NIH HHS P30 CA008748NIDA NIH HHS DA050923NIDA NIH HHS UG3 DA050923
6 · The paper itself

Abstract

BACKGROUND AND

objectivesSuffering adverse childhood experiences (ACEs) increases the probability of developing adult mental illness, addictions, and insecure attachment. This study determined how ACEs and insecure attachment are associated with each other, and how they may predict treatment engagement in an integrated dual diagnosis treatment clinic.

methodsA sample of n = 264 patients entering a university-affiliated addiction psychiatry clinic underwent diagnostic intakes supplemented by assessments of attachment styles (Anxious/Avoidant, using the 36-item Experiences in Close Relationships-Relationship Structures (ECR-RS) scale) and childhood adversity (10-item Adverse Childhood Experiences Questionnaire (ACE-Q) scale). Compliance with psychotherapy versus medication appointments was tracked for 6 months post intake.

resultsACE-Q scores (median of 4) were significantly associated with higher anxious and avoidant attachment scores and the number of mental health diagnoses. Only one in five patients obtained 75% or higher compliance rates with psychotherapy; two in five achieved 75% or higher compliance with medication appointments. Greater anxious attachment predicted lower show rates for both psychotherapy and medication appointments, whereas greater avoidant attachment predicted lower compliance for psychotherapy only. DISCUSSION AND

conclusionsThis study confirms the linkage of ACEs and insecure attachment patterns in dual-diagnosis patients seeking integrated addiction psychiatry care. Insecure attachment patterns differentially predicted lower appointment compliance, particularly for psychotherapies. SCIENTIFIC SIGNIFICANCE: Childhood trauma and associated adult attachment dysfunction warrant further investigation not only as causes and correlates of mental illness and addiction but also for improving treatment engagement, therapeutic attachments, and recovery outcomes.

Indexed as

Adverse Childhood ExperiencesMental DisordersObject AttachmentPatient ComplianceSubstance-Related DisordersAdultAppointments and SchedulesDiagnosis, Dual (Psychiatry)FemaleHumansMaleMiddle AgedOutpatientsPsychotherapyYoung Adult

Identifiers

PMID39921423
PMCPMC12036499

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.