ArticleThe Journal of pediatrics2025
Growth Characteristics at Time of Fontan Procedure and Their Association with Long-Term Outcomes.
Article in The Journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- What Limits Cardiorespiratory Fitness in Adolescents with Fontan Circulation: An Integrated Hemodynamic and Pulmonary Perspective.Pediatric cardiology · 2026Article
- Early Experience with the First Canadian Paediatric Fontan Long-Term Follow-up Clinic.Pediatric cardiology · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectiveTo assess whether somatic growth may predict long-term success after a Fontan procedure. STUDY
designThe National Death Index was used to track outcomes of Fontan procedures from 1982 through 2011, using data from the Pediatric Cardiac Care Consortium, a US-based registry. Kaplan-Meier plots and Cox models were used to compare outcomes by growth characteristics, adjusting for sex, dominant ventricle, and era.
resultsAmong 1461 patients (median age 3.12 years at Fontan evaluation), median z-scores indicated delayed growth: height-for-age z-score (HAZ) -0.66, weight-for-age z-score (WAZ) -0.81, and weight-for-height z-score (WHZ) -0.50. Systemic left ventricle (LV) patients had higher WAZ vs those with right (-0.66 vs -0.93, P < .01). Over 21.2 years of median follow-up through 2022, 78 in-hospital and 184 postdischarge deaths occurred. High WAZ tertile was associated with decreased in-hospital mortality or takedown (aOR vs low tertile: 0.54; 95% CI: 0.31-0.95, P = .03). Long-term survival was not universally linked to growth, but systemic LV patients with higher HAZ tertile had better 25-year survival (high 93.8% vs middle 92.2% and low 82.2%, P = .02). High HAZ and middle WAZ tertiles were associated with lower mortality (adjusted hazard ratio vs low tertiles: 0.42; 95% CI: 0.20-0.87, P = .02 and .52; 95% CI: 0.28-0.97, P = .04). Overweight (WHZ > 2) was associated with increased mortality (adjusted hazard ratio vs normal WHZ: 2.43; 95% CI: 1.15-5.14, P = .02).
conclusionsSuboptimal growth is prevalent after Fontan procedure. Higher weight correlates with improved perioperative outcomes, and taller height and balanced growth are associated with improved long-term survival, particularly in patients with a systemic LV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.