ReviewJournal of neuroimaging : official journal of the American Society of Neuroimaging
Technical Considerations in the TCD Evaluation of Cerebral Circulatory Arrest in Death by Neurological Criteria.
Review in Journal of neuroimaging : official journal of the American Society of Neuroimaging. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Paediatric and adult neurological point-of-care ultrasound: Review of the evidence, and the UK accreditation pathway.Journal of the Intensive Care Society · 2026Article
- Point-of-Care Transcranial Doppler Sonography at the Intensive Care Unit-A Practical Review of the Fundamentals.Journal of clinical medicine · 2026Review
- Second Transcranial Doppler to Confirm Cerebral Circulatory Arrest.Neurocritical care · 2025Article
- Transcranial ultrasound in the critically ill patient: a narrative review.Intensive care medicine experimental · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeAncillary testing is essential for diagnosing brain death/death by neurologic criteria (BD/DNC) when clinical determination (neurologic exam and apnea testing) cannot be fully or safely performed. Transcranial Doppler ultrasound (TCD) has been recommended as an ancillary test; however, the technical descriptions have been heterogeneous. We aimed to consolidate the technical considerations related to the use of TCD as an ancillary test in the evaluation of BD/DNC.
methodsWe performed a scoping review of the available literature from inception to December 2024. Articles describing TCD as an ancillary test for BD/DNC were included using appropriate Medical Subject Headings terms. The focus was on technical details and clinimetric properties of TCD (e.g., signal quality, frequency, gate, probe location, etc.). Technical categories were curated as full-text reviews were completed.
resultsWe reviewed 181 articles to extract technical descriptions of TCD under several categories. Image acquisition was divided into machine-related factors (59 studies, four questions), exam-related aspects (82 studies, 13 questions), and patient anatomical factors (19 studies, three questions). Image interpretation concerns were addressed in 50 studies (three questions). Patient-related clinical factors affecting TCD utility were addressed in 44 studies (seven questions). Legislative priorities were discussed in 19 studies; in 13 studies, authors commented on their recommendations for research priorities.
conclusionWe found significant inconsistencies and a lack of technical details described in the literature. Next steps include a national survey of current TCD protocols for BD/DNC evaluation, and an expert consensus guidelines report on the technical use of TCD as an ancillary test.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.