Evidence map›Paper›PMID 39920842›Full record

ArticleItalian journal of pediatrics2025

Determination of oral feeding skills in late preterm, early term, and full-term infants using the neonatal oral feeding monitor (NeoSAFE).

Ayse Ecevit, Balkar Erdogan, Deniz Anuk Ince, Meltem Aksu, Sezin Unal, Özden Turan, Ahmet Saracoglu, Aylin Tarcan

Registry-linked trialAbstract read
In one paragraph

Article in Italian journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07273266 (The Effect of Routine Versus Random Pacifier Administration Methods on Feeding Maturity in Preterm Infants), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07273266 narecruitingnot on this map

The Effect of Routine Versus Random Pacifier Administration Methods on Feeding Maturity in Preterm Infants

TypeinterventionalSponsorAcibadem UniversityRan2025 to 2026Enrolled62ConditionsPreterm, Feeding, Non Nutritive SuckingArmsRoutine NNS, Random NNS
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ayse EcevitFaculty of Medicine, Department of Pediatrics, Division of Neonatology, Baskent University, Ankara, Turkey.
Balkar ErdoganMiddle East Technical University, Technology Transfer Office (TTO) KuartisMED Medical Company, Ankara, Turkey.
Deniz Anuk InceFaculty of Medicine, Department of Pediatrics, Division of Neonatology, Baskent University, Ankara, Turkey.
Meltem AksuFaculty of Medicine, Department of Pediatrics, Division of Neonatology, Baskent University, Ankara, Turkey.
Sezin UnalFaculty of Medicine, Department of Pediatrics, Division of Neonatology, Baskent University, Ankara, Turkey. sezinunal@gmail.com.ORCID http://orcid.org/0000-0002-5124-4422
Özden TuranFaculty of Medicine, Department of Pediatrics, Division of Neonatology, Baskent University, Ankara, Turkey.
Ahmet SaracogluMiddle East Technical University, Technology Transfer Office (TTO) KuartisMED Medical Company, Ankara, Turkey.
Aylin TarcanMiddle East Technical University, Technology Transfer Office (TTO) KuartisMED Medical Company, Ankara, Turkey.

Funding

Baskent Üniversitesi Project number: KA23/183
6 · The paper itself

Abstract

backgroundMature oral feeding is a complex function involving numerous muscles and nerves, typically developing between the postmenstrual age of 34-36 weeks in newborn infants. The objective of this study was to analyze the oral feeding skills of healthy late preterm, early term, and full-term infants using a neonatal oral feeding monitor.

methodsWe used the oral feeding parameters reported by NeoSAFE which is a certified medical device, to assess the swallowing and swallow-respiration coordination in newborn infants. Oral feeding parameters were recorded over a 2-minutes long bottle-feeding session. The total swallow count, swallow time, maximum rhythmic swallows, resting interval duration, time between rhythmic swallows and inspiration after swallow count were recorded by NeoSAFE. We planned to examine the relationship of oral feeding parameters according to the gestational age. We also investigated whether the coordination of swallowing and respiration changes with respect to gestational age in newborn infants.

resultsA total of 88 infants were included; 34 late preterm, 34 early term, and 20 full term. The gestational age was found to have significant negative correlation with the average time between rhythmic swallows and positive correlation with the swallow time. Feeding volume was found to have a negative correlation with the resting interval duration and average time between rhythmic swallows. It was also found that the feeding volume has a positive correlation with total swallow count, swallow time, maximum rhythmic swallow and inspirium after swallow count.

conclusionAlthough the oral feeding skills of infants at 34 weeks gestation are still developing, this study identified differences in oral feeding skills among late preterm, early term, and full-term infants when assessed using a neonatal swallow and respiration detection system. However, conducting larger cohort studies using NeoSAFE would be beneficial for guiding oral feeding approaches in infants.

trial registrationNot applicable.

Indexed as

Bottle FeedingDeglutitionFeeding BehaviorInfant, PrematureSucking BehaviorFemaleGestational AgeHumansInfant, NewbornMaleMonitoring, PhysiologicDeglutitionDeglutition disordersNeoSAFENewborn feeding assessmentNewborn infantsOral feeding skillsPretermSwallow detectionSwallow respiration coordination assessment

Identifiers

PMID39920842
PMCPMC11806788

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.