Evidence map›Paper›PMID 39920533›Full record

ArticleThe protein journal2025

The Effect of Inhaled Ozone Therapy in Two-Hit Rat Model of Lipopolysaccharides-Induced Acute Lung Injury and Bleomycin-Induced Pulmonary Fibrosis.

Mine Celik, Mehmet Koca, Zekai Halici, Taha Tavaci, Hamza Halici, Mustafa Ozkaraca, Zeynep Karakoy, Zafer Bayraktutan

Abstract read
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In one paragraph

Article in The protein journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mine CelikDepartment of Anesthesiology and Reanimation, Istanbul Provincial Health Directorate, Istanbul Haseki Education And Research Hospital, Istanbul, 34130, Turkey. mine.celik74@gmail.com.ORCID http://orcid.org/0000-0002-4718-0921
Mehmet KocaManagement Services General Directorate, Ministry of Health, 06800, Ankara, Turkey.ORCID http://orcid.org/0000-0003-1108-3182
Zekai HaliciDepartment of Pharmacology, Faculty of Medicine, Ataturk University, 25240, Erzurum, Turkey.ORCID http://orcid.org/0000-0001-6854-6059
Taha TavaciDepartment of Pharmacology, Faculty of Medicine, Sakarya University, 54050, Sakarya, Turkey.ORCID http://orcid.org/0000-0002-8284-8317
Hamza HaliciDepartment of Hınıs Vocational Training School, Ataturk University, 25600, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-2028-6603
Mustafa OzkaracaDepartment of Pathology, Faculty of Veterinarian, Cumhuriyet University, 58070, Sivas, Turkey.ORCID http://orcid.org/0000-0001-9765-4569
Zeynep KarakoyDepartment of Pharmacology, Faculty of Pharmacy, Erzincan Binali Yıldırım University, 24002, Erzincan, Turkey.ORCID http://orcid.org/0000-0002-4281-0103
Zafer BayraktutanDepartment of Biochemistry, Faculty of Medicine, Ataturk University, 25040, Erzurum, Turkey.ORCID http://orcid.org/0000-0002-4324-5943

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Considering the limited treatment options for acute lung injury (ALI) and pulmonary fibrosis (PF), ozone treatment may be promising as a new immunological agent with its ability to modulate cytokines and interferons. We aimed to investigate the effects of inhaled ozone therapy on both ALI and PF in rat models. A total of 48 albino Wistar male rats were included in the study. Lipopolysaccharide (LPS) was used to induce the ALI model, and bleomycin was used for the PF model. The effects of inhaled ozone (O

Indexed as

Acute Lung InjuryBleomycinOzonePulmonary FibrosisAdministration, InhalationAnimalsCytokinesDisease Models, AnimalLipopolysaccharidesLungMaleRatsRats, WistarBleomycinCytokinesLipopolysaccharidesOzoneAcute lung InjuryCytokinesInhaled Ozone TherapyOzonePulmonary Fibrosis

Identifiers

PMID39920533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.