ArticleLasers in medical science2025
Efficacy and safety of microfocused ultrasound for temporary eyebrow lift and glabellar wrinkle reduction.
Article in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Efficacy and Safety of 1.5- and 3.0-mm High-Intensity Focused Ultrasound for Eyebrow Lifting in Korean Adults: A Prospective Randomized Split-Face Study.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2026Trial
- High-Intensity Focused Ultrasound for Facial Rejuvenation and Body Contouring: A Bibliometric Analysis of Efficacy and Safety Studies.Aesthetic surgery journal. Open forum · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Microfocused ultrasound (MFU) is a noninvasive treatment method that is widely used for skin tightening. In this study, we investigated the efficacy and safety of a novel MFU device for temporary eyebrow lifting and glabellar wrinkle reduction. In this prospective, single-center, single-arm, and open-label study, 38 patients were enrolled. Each patient was treated with MFU at the forehead and lateral eye areas. The treatment efficacy was measured at weeks 4, 8, 12, and 16 by calculating the average eyebrow height (AEH), maximal eyebrow height (MEH), patient satisfaction score, and glabellar Line Scale (GLS) score. Moreover, adverse events were recorded. The AEH was elevated with a mean difference of 1.99 mm at week 4 and remained elevated at week 16 with a mean difference of 1.57 mm. (P < 0.0001, respectively). In addition, the mean MEH increased by 2.21 mm at week 4 and by 1.63 mm at week 16 (P < 0.0001, respectively). Glabellar wrinkles were temporarily alleviated in some patients, with 71.05% of patients showing an improvement of one point or more in their GLS score at week 4. No serious adverse events were reported. MFU is an effective and safe treatment for temporary eyebrow lifting and glabellar wrinkle reduction.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.