Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Implementation of pharmaceutical strategies using the PDCA cycle for standardized management of cancer pain medications.
Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Study protocol for a prospective, multicenter, single-arm study investigating the impact of the implementation of standardized hyperkalemia management in chronic kidney disease patients.BMC nephrology · 2026Article
- Application of the PDCA cycle management in quality improvement of endotracheal intubation in emergency department among standardised training residents.BMC medical education · 2026Article
- The impact of pharmacist-led medication therapy management on the efficacy of cancer pain control: a pre-post interventional study.Journal of pharmaceutical health care and sciences · 2026Article
- LLM-driven collaborative framework for knowledge-enhanced cancer pain assessment and management.NPJ digital medicine · 2026Article
- Effect of PDCA cycle on critical value management in primary healthcare institutions: an interrupted time series study.Frontiers in health services · 2026Article
- [Sub-committee of Anesthesiology of Guangzhou Integrated Traditional Chinese and Western Medicine Society].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe three-step analgesic ladder, recommended by the World Health Organization (WHO), serves as a guideline for managing cancer pain, progressing from non-opioids to weak opioids and strong opioids based on pain intensity. Despite its widespread use, challenges in standardizing its application persist, impacting medication safety and efficacy. This study aimed to implement the PDCA (Plan-Do-Check-Act) cycle in hospital inpatient pharmacies to improve the management and compliance of the three-step analgesic ladder for cancer pain patients.
methodsA mixed-methods study design combining retrospective and prospective components was employed. Retrospective data on prescription compliance for three-step analgesics were collected from June 2021 to March 2022 (pre-implementation). The prospective randomized cohort study enrolled 160 advanced cancer patients from June 2022 to March 2023 (intervention and control groups). Interventions included paperless prescription management, enhanced patient education, and structured follow-ups.
resultsThe prescription compliance rate improved significantly from 72.32% before implementation to 92.92% after implementation (P < 0.05). Satisfaction rates among medical staff with the management process increased from 81.09 to 94.22%, indicating enhanced efficiency and accuracy. Satisfaction rates reflected healthcare professionals' evaluation of improved prescription practices and reduced workload. Pain intensity, measured by the visual analog scale (VAS), decreased significantly in the intervention group compared to the control group (2.26 ± 0.78 vs. 3.07 ± 0.15; P < 0.01).
conclusionsThe implementation of the PDCA cycle significantly improved compliance with the WHO three-step analgesic ladder, enhanced pain management outcomes, and increased satisfaction among healthcare professionals. Future studies should explore integrating patient-specific assessments to optimize individualized pain management strategies.
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