Evidence map›Paper›PMID 39920293›Full record

ArticleScientific reports2025

Detection of serum composition in pediatric inflammatory multisystem syndrome associated with SARS-CoV-2 and the response for the treatment by FTIR.

Joanna Depciuch, Izabela Sieminska, Pawel Jakubczyk, Bartosz Klebowski, Katarzyna Ptak, Izabela Szymońska, Przemko Kwinta, Maciej Siedlar, Jan Jakub Kęsik, Magdalena Parlinska-Wojtan and 1 more

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joanna DepciuchInstitute of Nuclear Physics, Polish Academy of Sciences, Walerego Eljasza - Radzikowskiego 152, Kraków, 31-342, Poland. joanna.depciuch@ifj.edu.pl.
Izabela SieminskaInstitute of Veterinary Sciences, University Center of Veterinary Medicine JU-AU, University of Agriculture in Krakow, Mickiewicza Av. 24/28, Krakow, 30-059, Poland.
Pawel JakubczykInstitute of Physics, University of Rzeszow, al. Rejtana 16c, Rzeszów, 35-959, Poland.
Bartosz KlebowskiInstitute of Nuclear Physics, Polish Academy of Sciences, Walerego Eljasza - Radzikowskiego 152, Kraków, 31-342, Poland.
Katarzyna PtakDepartment of Pediatrics, Jagiellonian University Medical College, Wielicka Str. 265, Krakow, 30-663, Poland.
Izabela SzymońskaDepartment of Pediatrics, Jagiellonian University Medical College, Wielicka Str. 265, Krakow, 30-663, Poland.
Przemko KwintaDepartment of Pediatrics, Jagiellonian University Medical College, Wielicka Str. 265, Krakow, 30-663, Poland.
Maciej SiedlarDepartment of Clinical Immunology, Chair of Clinical Immunology and Transplantology, Jagiellonian University Medical College, Wielicka Str. 265, Krakow, 30-663, Poland.
Jan Jakub KęsikDepartment of Vascular Surgery and Angiology, Medical University of Lublin, Lublin, Poland.
Magdalena Parlinska-WojtanInstitute of Nuclear Physics, Polish Academy of Sciences, Walerego Eljasza - Radzikowskiego 152, Kraków, 31-342, Poland.
Jarek BaranDepartment of Clinical Immunology, Chair of Clinical Immunology and Transplantology, Jagiellonian University Medical College, Wielicka Str. 265, Krakow, 30-663, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pediatric Inflammatory Multisystem Syndrome (PIMS-TS), associated with SARS-CoV-2 infection, is a severe complication after COVID-19 in children. It is caused by the immune reaction to SARS-CoV-2, and usually appears three to six weeks after the infection. Unfortunately, PIMS causes non-specific symptoms, which makes its diagnosis and treatment difficult. In this paper, we propose Fourier Transform InfraRed spectrometry (FTIR) to identify chemical changes in blood serum of children induced by PIMS and caused by subsequent treatment of the syndrome. The results suggest that although the Principal Component Analysis (PCA) of FTIR data did not allow for differentiation of healthy children and children with PIMS before and after the treatment, the implementation of Support Vector Machine (SVM) showed that the accuracy of the FTIR region between 800 cm

Indexed as

COVID-19Systemic Inflammatory Response SyndromeAdolescentBiomarkersChildChild, PreschoolC-Reactive ProteinFemaleHumansInfantMalePrincipal Component AnalysisSARS-CoV-2Spectroscopy, Fourier Transform InfraredSupport Vector MachineBiomarkersC-Reactive ProteinFTIRLiquid biopsyMachine learningPIMSSerum marker

Identifiers

PMID39920293
PMCPMC11805954

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.