Evidence map›Paper›PMID 39920207›Full record

ArticleScientific reports2025

Direct current electrical fields inhibit cancer cell motility in microchannel confinements.

Benjamin Karem Naggay, Saeed Khomeijani Farahani, Xu Gao, Andrew Holle, Ralf Kemkemer

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin Karem NaggayDepartment of Life Sciences, Reutlingen University, 72762, Reutlingen, Germany.
Saeed Khomeijani FarahaniCharité Campus Benjamin Franklin, Charité-Universitätsmedizin Berlin, 12203, Berlin, Germany.
Xu GaoDepartment of Biomedical Engineering, National University of Singapore, Singapore, 117411, Singapore.
Andrew HolleDepartment of Biomedical Engineering, National University of Singapore, Singapore, 117411, Singapore.
Ralf KemkemerDepartment of Life Sciences, Reutlingen University, 72762, Reutlingen, Germany. ralf.kemkemer@reutlingen-university.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The capability of cells to sense and respond to endogenous electrical fields plays a crucial role in processes like nerve regeneration, wound healing, and development. In vitro, many cell types respond to electrical fields by migrating along the corresponding electrical field vectors. This process is known as galvano- or electrotaxis. Here we report on the combined impact of micro-confinements and direct current electrical fields (dcEFs) on the motility of MDA-MB-231 human breast cancer cells using a self-developed, easy-to-use platform with microchannels ranging from 3

Indexed as

Breast NeoplasmsCell MovementElectricityCell Line, TumorFemaleHumans

Identifiers

PMID39920207
PMCPMC11806051

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.