Evidence map›Paper›PMID 39920046›Full record

ArticleBMJ open2025

Family-focused intervention programme to foster adolescent mental health and well-being: protocol for a multicountry cluster randomised factorial trial (FLOURISH Phase 2).

Antonio Piolanti, Janina Mueller, Franziska Waller, Nina Heinrichs, Judit Simon, Yulia Shenderovich, Swetha Sampathkumar, Dennis Wienand, Marija Raleva, Ivo Kunovski and 4 more

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06562244 (A Family-focused Intervention Program to Foster Adolescent Mental Health and Well-being), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06562244 nacompletednot on this map

A Family-focused Intervention Program to Foster Adolescent Mental Health and Well-being: Protocol for a Multi-country Cluster Randomized Factorial Trial (FLOURISH Phase 2)

TypeinterventionalSponsorUniversity of KlagenfurtRan2024 to 2025Enrolled1,316ConditionsAdolescent - Emotional Problem, Parent-Child Relations, Family Functioning, Well-Being, PsychologicalArmsParenting for Lifelong Health for Parents and Teens (PLH), Helping Adolescents Thrive comics, I Support My Friends
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Antonio PiolantiDepartment of Health Psychology, University of Klagenfurt, Klagenfurt, Austria.ORCID http://orcid.org/0000-0002-0613-0696
Janina MuellerDepartment of Health Psychology, University of Klagenfurt, Klagenfurt, Austria.ORCID http://orcid.org/0000-0002-5005-2218
Franziska WallerDepartment of Health Psychology, University of Klagenfurt, Klagenfurt, Austria.
Nina HeinrichsDepartment of Psychology, Bielefeld University, Bielefeld, Germany.ORCID http://orcid.org/0000-0002-8301-5798
Judit SimonDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0001-9279-8627
Yulia ShenderovichCentre for Development, Evaluation, Complexity, and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-0254-3397
Swetha SampathkumarCentre for Development, Evaluation, Complexity, and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0001-6820-9183
Dennis WienandDepartment of Health Economics, Center for Public Health, Medical University of Vienna, Vienna, Austria.ORCID http://orcid.org/0000-0002-5183-1352
Marija RalevaInstitute for Marriage, Family, and Systemic Practice - ALTERNATIVA, Skopje, North Macedonia.
Ivo KunovskiInstitute for Marriage, Family, and Systemic Practice - ALTERNATIVA, Skopje, North Macedonia.
Viorel BabiiAsociatia Obsteasca Sanatate Pentru Tineri (Health for Youth Association), Chisinau, Republic of Moldova.
Xiang ZhaoDepartment of Health Psychology, University of Klagenfurt, Klagenfurt, Austria.ORCID http://orcid.org/0000-0003-1054-9462
Graham MooreCentre for Development, Evaluation, Complexity, and Implementation in Public Health Improvement (DECIPHer), School of Social Sciences, Cardiff University, Cardiff, UK.ORCID http://orcid.org/0000-0002-6136-3978
Heather M ForanDepartment of Health Psychology, University of Klagenfurt, Klagenfurt, Austria heather.foran@aau.at.ORCID http://orcid.org/0000-0001-6659-5500

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdolescent mental health problems represent a significant global health issue, particularly in low- and middle-income countries, such as the Republic of North Macedonia and the Republic of Moldova. Effective and scalable interventions are urgently needed to address these challenges. METHODS AND ANALYSIS: This protocol outlines a multicountry cluster randomised factorial trial, implemented according to the multiphase optimisation strategy (Phase 2), which evaluates the effectiveness and costs of three add-on components for the Parenting for Lifelong Health for Parents and Teens programme: adolescent mental health tools based on UNICEFs Helping Adolescents Thrive comics, adolescent peer support based on UNICEFs 'I Support My Friends' intervention and engagement booster designed to enhance attendance and programme completion through incentives. The study will recruit 720 families and involve 64 clusters in North Macedonia and Moldova. Primary outcomes will include adolescent internalising problems and social support, family functioning and attendance during the programme. Secondary outcomes will assess broader aspects of mental health among caregivers and adolescents, as well as implementation and cost outcomes. Data will be collected at baseline and postintervention, approximately, 8 weeks later. Statistical analyses will include regression models to assess the main and interaction effects of the intervention components and cost analyses. ETHICS AND DISSEMINATION: The study received ethical approval from the University of Klagenfurt in Austria (approval number: 2023-013), the Medical Faculty at St. Cyril and Methodius University in North Macedonia (approval number: 03-2144/4) and the National Committee of Ethical Expertise for Clinical Trials in Moldova (approval number: 1476). The results will be disseminated through peer-reviewed journals, conferences, webinars in multiple languages, regional forums, stakeholder meetings with policymakers and practitioners, public communication through media engagement and open access platforms, including data sharing and early release of findings. TRIAL REGISTRATION DETAILS: Trial registration: NCT06562244; Project page: https://www.flourish-study.org/about.html.

Indexed as

FamilyMental HealthAdolescentClinical Trials, Phase II as TopicFemaleHumansMaleMoldovaMulticenter Studies as TopicParentingParentsRandomized Controlled Trials as TopicRepublic of North MacedoniaSocial SupportAdolescentsImplementation ScienceMENTAL HEALTH

Identifiers

PMID39920046
PMCPMC11808879

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.