ArticleInternational dental journal2025
Comparative Effect of Different Preoperative Antibiotics on Dental Implant Failure: A Retrospective Cohort Study.
Article in International dental journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Impact of interventional periodontal therapy on the longevity of failing dental implants: A retrospective analysis.Medicina oral, patologia oral y cirugia bucal · 2026Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a lack of standardized guidelines for the prescription of antibiotics prior to implant surgery. The purpose of this study was to compare the effect of different antibiotics preoperatively on dental implant treatment outcome.
methodsThis retrospective analysis involved a cohort of patients who received dental implant treatment at ten university dental clinics participating in the BigMouth network. All patients records who received antibiotic medication prior to implant surgery including amoxicillin, amoxicillin/clavulanic acid, clindamycin, azithromycin, ciprofloxacin, doxycycline, and metronidazole were analysed. The treatment outcome was assessed as a binary outcome, classified as either survival or failure of the implant.
resultsA total of 41,135 implants inserted in 17,483 individuals and followed-up for a mean time of 81 ± 52.33 months. The implant failure rate was 3% at the patient level and 1.6% at the implant level. Hispanic and non-Hispanic ethnic groups showed higher likelihood to have an implant failure than other races, as well as White and African-American races, were more likely to experience implant loss compared to Hispanic patients. Implants placed in patients who received Ciprofloxacin preoperatively showed significantly lower cumulative survival implant time than those who had amoxicillin.
conclusionsWithin the limitations of this retrospective study, premedication with Ciprofloxacin led to statistically significant lower implant survival time than with amoxicillin. Future prospective randomized clinical trials are needed to validate the present findings.
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