Evidence map›Paper›PMID 39919830›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

Neuroendocrine Control of Synaptic Transmission by PHAC-1 in

Aikaterini Stratigi, Miguel Soler-García, Mia Krout, Shikha Shukla, Mario De Bono, Janet E Richmond, Patrick Laurent

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aikaterini StratigiLaboratory of Neurophysiology, ULB Institute for Neuroscience, Université Libre de Bruxelles, Brussels 1070, Belgium.
Miguel Soler-GarcíaLaboratory of Neurophysiology, ULB Institute for Neuroscience, Université Libre de Bruxelles, Brussels 1070, Belgium.ORCID 0009-0003-4218-6296
Mia KroutDepartment of Biological Sciences, University of Illinois Chicago, Chicago, Illinois 60607.ORCID 0000-0001-6328-1477
Shikha ShuklaLaboratory of Neurophysiology, ULB Institute for Neuroscience, Université Libre de Bruxelles, Brussels 1070, Belgium.ORCID 0000-0001-8322-1703
Mario De BonoInstitute of Science and Technology, Klosterneuburg 3400, Austria.
Janet E RichmondDepartment of Biological Sciences, University of Illinois Chicago, Chicago, Illinois 60607.
Patrick LaurentLaboratory of Neurophysiology, ULB Institute for Neuroscience, Université Libre de Bruxelles, Brussels 1070, Belgium patrick.laurent@ulb.be.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

A dynamic interplay between fast synaptic signals and slower neuromodulatory signals controls the excitatory/inhibitory (E/I) balance within neuronal circuits. The mechanisms by which neuropeptide signaling is regulated to maintain E/I balance remain uncertain. We designed a genetic screen to isolate genes involved in the peptidergic maintenance of the E/I balance in the

Indexed as

Caenorhabditis elegans ProteinsProtein Phosphatase 1SynapsinsSynaptic TransmissionAnimalsAnimals, Genetically ModifiedCaenorhabditis elegansHumansNeuropeptidesSignal TransductionCaenorhabditis elegans ProteinsNeuropeptidesProtein Phosphatase 1Synapsinsdevelopmental and epileptic encephalopathy-70neuromodulationneuropeptidephactr1synapsinsynaptic transmission

Identifiers

PMID39919830
PMCPMC11949478

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.