Evidence map›Paper›PMID 39919828›Full record

ArticleGenes & development2025

Hao-Fountain syndrome protein USP7 controls neuronal differentiation via BCOR-ncPRC1.1.

Joyce Wolf van der Meer, Axelle Larue, Jan A van der Knaap, Gillian E Chalkley, Ayestha Sijm, Leila Beikmohammadi, Elena N Kozhevnikova, Aniek van der Vaart, Ben C Tilly, Karel Bezstarosti and 10 more

Abstract read
In one paragraph

Article in Genes & development, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Joyce Wolf van der MeerDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0000-0001-6077-8170
Axelle LaruePatrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT9 7AE, United Kingdom.ORCID 0000-0001-9846-9955
Jan A van der KnaapDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0000-0002-9175-6086
Gillian E ChalkleyDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0009-0000-1023-5450
Ayestha SijmDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0000-0002-7304-9062
Leila BeikmohammadiDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Elena N KozhevnikovaDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Aniek van der VaartDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Ben C TillyDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Karel BezstarostiDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Dick H W DekkersDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Wouter A S DoffDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
P Jantine van de Wetering-TielemanDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Kristina LankoDepartment of Clinical Genetics, Erasmus MC University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0000-0002-0749-0079
Tahsin Stefan BarakatDepartment of Clinical Genetics, Erasmus MC University Medical Center, 3025 GD Rotterdam, The Netherlands.ORCID 0000-0003-1231-1562
Tim AllertzDepartment of Cell Biology, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Jeffrey van HarenDepartment of Cell Biology, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands.
Jeroen A A DemmersDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands; c.verrijzer@erasmusmc.nl j.demmers@erasmusmc.nl y.atlasi@qub.ac.uk.ORCID 0000-0002-8757-9611
Yaser AtlasiPatrick G Johnston Centre for Cancer Research, Queen's University Belfast, Belfast BT9 7AE, United Kingdom; c.verrijzer@erasmusmc.nl j.demmers@erasmusmc.nl y.atlasi@qub.ac.uk.ORCID 0000-0002-7350-1784
C Peter VerrijzerDepartment of Biochemistry, Erasmus University Medical Center, 3025 GD Rotterdam, The Netherlands; c.verrijzer@erasmusmc.nl j.demmers@erasmusmc.nl y.atlasi@qub.ac.uk.ORCID 0000-0002-6476-3264

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pathogenic variants in the ubiquitin-specific protease 7 (

Indexed as

Cell DifferentiationNeuronsProto-Oncogene ProteinsRepressor ProteinsUbiquitin-Specific Peptidase 7AnimalsCell Line, TumorGene Expression Regulation, DevelopmentalHumansMiceNeural Stem CellsBCOR protein, humanProto-Oncogene ProteinsRepressor ProteinsUbiquitin-Specific Peptidase 7USP7 protein, humanchromatinHao-Fountain syndromeneurodevelopmentPolycombtranscriptionubiquitinUSP7

Identifiers

PMID39919828
PMCPMC11875088

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.