Evidence map›Paper›PMID 39919817›Full record

ArticleeNeuro2025

Modulation of Extrinsic and Intrinsic Signaling Together with Neuronal Activation Enhances Forelimb Motor Recovery after Cervical Spinal Cord Injury.

Hirohide Takatani, Naoki Fujita, Fumiyasu Imai, Yutaka Yoshida

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Cutting-edge technologies in neural regeneration.Cell regeneration (London, England) · 2025
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Hirohide TakataniNeural Connectivity Development in Physiology and Disease Laboratory, Burke Neurological Institute, White Plains, New York 10605.
Naoki FujitaLaboratory of Veterinary Surgery, Graduate School of Agriculture and Life Sciences, The University of Tokyo, Bunkyo-ku, Tokyo 113-0032, Japan.
Fumiyasu ImaiNeural Connectivity Development in Physiology and Disease Laboratory, Burke Neurological Institute, White Plains, New York 10605.
Yutaka YoshidaNeural Connectivity Development in Physiology and Disease Laboratory, Burke Neurological Institute, White Plains, New York 10605 yoy4001@med.cornell.edu.ORCID https://orcid.org/0000-0003-0664-0888

Funding

Synapse elimination in the central nervous systemR01NS093002 · NINDS · WINIFRED MASTERSON BURKE MED RES INST · PI YOSHIDA, YUTAKA · 2015 to 2024
$4.6M
Advanced, multi-function, inverted confocal microscope for BNI Structural and Functional Imaging CoreS10OD028547 · OD · WINIFRED MASTERSON BURKE MED RES INST · PI HOLLIS, EDMUND R · 2020 to 2020
$530k
An advanced, high-throughput imaging system for the BNI Structural and Functional Imaging CoreS10OD036432 · OD · WINIFRED MASTERSON BURKE MED RES INST · PI HOLLIS, EDMUND R · 2024 to 2024
$273k
NIH HHS S10 OD028547NIH HHS S10 OD036432NINDS NIH HHS R01 NS093002
6 · The paper itself

Abstract

Singular strategies for promoting axon regeneration and motor recovery after spinal cord injury (SCI) have been attempted with limited success. For instance, the deletion of

Indexed as

ForelimbNerve RegenerationRecovery of FunctionSignal TransductionSpinal Cord InjuriesAnimalsAxonsCervical CordFemaleMiceMice, Inbred C57BLMotor ActivityPTEN PhosphohydrolasePyramidal TractsrhoA GTP-Binding ProteinPTEN PhosphohydrolasePten protein, mouserhoA GTP-Binding ProteinRhoA protein, mousecorticospinal tracthM3DqPtenRhoAspinal cord injury

Identifiers

PMID39919817
PMCPMC11881905

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.