Evidence map›Paper›PMID 39919171›Full record

ArticleScience advances2025

Centrioles generate two scaffolds with distinct biophysical properties to build mitotic centrosomes.

Siu-Shing Wong, Joao M Monteiro, Chia-Chun Chang, Min Peng, Nada Mohamad, Thomas L Steinacker, Bocheng Xiao, Saroj Saurya, Alan Wainman, Jordan W Raff

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siu-Shing WongSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-5327-8466
Joao M MonteiroSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0001-5181-1397
Chia-Chun ChangSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0001-7942-6300
Min PengSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-5675-0607
Nada MohamadSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-0009-1358
Thomas L SteinackerSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-7244-5610
Bocheng XiaoSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0009-0000-9952-9198
Saroj SauryaSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0003-4057-0123
Alan WainmanSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-6292-4183
Jordan W RaffSir William Dunn School of Pathology, University of Oxford, Oxford OX1 3RE, United Kingdom.ORCID 0000-0002-4689-1297

Funding

Wellcome Trust
6 · The paper itself

Abstract

Mitotic centrosomes assemble when centrioles recruit large amounts of pericentriolar material (PCM) around themselves. The PCM comprises hundreds of proteins, and there is much debate about its physical nature. Here, we show that

Indexed as

CentriolesCentrosomeMitosisAnimalsAurora Kinase ACell Cycle ProteinsCytoskeletal ProteinsDrosophila melanogasterDrosophila ProteinsHomeodomain ProteinsHumansProtein Serine-Threonine KinasesAurora Kinase ACell Cycle Proteinscnn protein, DrosophilaCytoskeletal ProteinsDrosophila ProteinsHomeodomain Proteinspolo protein, DrosophilaProtein Serine-Threonine KinasesSPD-2 protein, Drosophila

Identifiers

PMID39919171
PMCPMC11804907

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.