Evidence map›Paper›PMID 39919167›Full record

ArticleThe Journal of bone and joint surgery. American volume2025

Clinical, Functional, Sports Participation, and Osteoarthritis Outcomes After ACL Injury: Ten-Year Follow-up Study of the Delaware-Oslo ACL Cohort Treatment Algorithm.

Anouk P Urhausen, Marie Pedersen, Hege Grindem, Naoaki Ito, Elanna K Arhos, Ragnhild Gunderson, Arne Kristian Aune, Lars Engebretsen, Michael J Axe, Karin Grävare Silbernagel and 3 more

Abstract read
In one paragraph

Article in The Journal of bone and joint surgery. American volume, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anouk P UrhausenDepartment of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0002-4409-1501
Marie PedersenDepartment of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0001-5768-0025
Hege GrindemOslo Sports Trauma Research Center, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0003-2121-0827
Naoaki ItoDepartment of Physical Therapy, University of Delaware, Newark, Delaware.ORCID 0000-0003-4166-5319
Elanna K ArhosDepartment of Physical Therapy and Human Movement Sciences, Northwestern University, Chicago, Illinois.ORCID 0000-0001-9829-1624
Ragnhild GundersonDepartment of Radiology, Oslo University Hospital, Oslo, Norway.ORCID 0000-0003-0603-4466
Arne Kristian AuneOrthopaedic Department, Aleris Hospital, Drammen, Norway.
Lars EngebretsenOslo Sports Trauma Research Center, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0003-2294-921
Michael J AxeDepartment of Physical Therapy, University of Delaware, Newark, Delaware.ORCID 0000-0002-9541-1843
Karin Grävare SilbernagelDepartment of Physical Therapy, University of Delaware, Newark, Delaware.ORCID 0000-0001-7566-407
Inger HolmDivision of Orthopedic Surgery, Oslo University Hospital, Oslo, Norway.ORCID 0000-0002-3476-9059
Lynn Snyder-MacklerDepartment of Physical Therapy, University of Delaware, Newark, Delaware.ORCID 0000-0002-1767-7910
May Arna RisbergDepartment of Sports Medicine, Norwegian School of Sport Sciences, Oslo, Norway.ORCID 0000-0002-9511-1314

Funding

Dynamic Stability in the ACL Injured KneeR37HD037985 · NICHD · UNIVERSITY OF DELAWARE · PI GRAVARE SILBERNAGEL, KARIN M E · 2012 to 2021
$4.2M
Dynamic Stability of the ACL Deficient KneeR01HD037985 · NICHD · UNIVERSITY OF DELAWARE · PI SNYDER-MACKLER, LYNN · 2001 to 2010
$2.6M
NICHD NIH HHS R01 HD037985NICHD NIH HHS R37 HD037985
6 · The paper itself

Abstract

backgroundAnterior cruciate ligament reconstruction (ACLR) is often recommended for treatment of an ACL injury; however, the literature reports similar outcomes for those undergoing rehabilitation alone. We assessed the clinical, functional, sports participation, and osteoarthritis outcomes following our treatment algorithm, and compared 10-year outcomes among participants who chose progressive rehabilitation alone, early ACLR, or delayed ACLR.

methodsWe included 276 participants who had a unilateral ACL injury without substantial concomitant knee injuries in a prospective cohort study. Treatment choice was based on shared decision-making after a 5-week progressive rehabilitation program. At the 10-year follow-up, we assessed patient-reported outcomes (International Knee Documentation Committee Subjective Knee Form [IKDC-SKF], Knee injury and Osteoarthritis Outcome Score [KOOS], and patient acceptable symptom state [PASS] achievement), quadriceps strength, hop performance, sports participation, and weight-bearing radiographs.

resultsSixty-nine percent of the participants (191 participants; 99 male and 92 female; 6 African American, 7 Asian, 59 Caucasian, 119 unknown) attended the 10-year follow-up, including 98% (53) of 54 participants who had rehabilitation alone, 68% (114) of 167 with early ACLR, and 69% (24) of 35 with delayed ACLR. Among the entire cohort, 78% (126 of 162) reported having a PASS, 72% (109 of 151) had symmetrical quadriceps strength, ≥85% (≥116 of ≤137) had a symmetrical hop performance, 93% (162 of 174) were still engaged in some kind of sports, only 1% (1 of 139) had symptomatic osteoarthritis, and 12% (17 of 139) had radiographic evidence of osteoarthritis. We found similar outcomes after rehabilitation alone and early ACLR. The participants who underwent delayed ACLR had similar outcomes to the other 2 groups except for significantly lower KOOS Sports scores, KOOS Quality of Life scores, and hop performance (p ≤ 0.03). Participants who had rehabilitation alone were older, less active, and more likely to have concomitant lateral meniscal injuries than those who underwent ACLR.

conclusionsParticipants who followed our treatment algorithm after ACL injury had high percentages of satisfaction and of symmetrical quadriceps strength and hop performance, high sports participation rates, and low prevalences of osteoarthritis. Participants who chose progressive rehabilitation alone, despite being older and less active, had similar clinical, functional, sports participation, and osteoarthritis outcomes compared with those who chose early ACLR. Participants who underwent delayed ACLR scored lower on KOOS Sports, KOOS Quality of Life, and hop performance compared with both other groups. LEVEL OF EVIDENCE: Therapeutic Level II . See Instructions for Authors for a complete description of levels of evidence.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionOsteoarthritis, KneeAdolescentAdultAlgorithmsFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient Reported Outcome MeasuresProspective StudiesRecovery of FunctionReturn to SportTreatment Outcome

Identifiers

PMID39919167
PMCPMC12003075

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.