Evidence map›Paper›PMID 39919140›Full record

ArticlePloS one2025

Advanced retinal disease detection from OCT images using a hybrid squeeze and excitation enhanced model.

Gülcan Gencer, Kerem Gencer

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

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6citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Gülcan GencerDepartment of Biostatistics and Medical Informatics, Faculty of Medicine, Afyonkarahisar Health Sciences University, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-3543-041X
Kerem GencerDepartment of Computer Engineering, Faculty of Engineering, Afyon Kocatepe University, Afyonkarahisar, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRetinal problems are critical because they can cause severe vision loss if not treated. Traditional methods for diagnosing retinal disorders often rely heavily on manual interpretation of optical coherence tomography (OCT) images, which can be time-consuming and dependent on the expertise of ophthalmologists. This leads to challenges in early diagnosis, especially as retinal diseases like diabetic macular edema (DME), Drusen, and Choroidal neovascularization (CNV) become more prevalent. OCT helps ophthalmologists diagnose patients more accurately by allowing for early detection. This paper offers a hybrid SE (Squeeze-and-Excitation)-Enhanced Hybrid Model for detecting retinal disorders from OCT images, including DME, Drusen, and CNV, using artificial intelligence and deep learning.

methodsThe model integrates SE blocks with EfficientNetB0 and Xception architectures, which provide high success in image classification tasks. EfficientNetB0 achieves high accuracy with fewer parameters through model scaling strategies, while Xception offers powerful feature extraction using deep separable convolutions. The combination of these architectures enhances both the efficiency and classification performance of the model, enabling more accurate detection of retinal disorders from OCT images. Additionally, SE blocks increase the representational ability of the network by adaptively recalibrating per-channel feature responses.

resultsThe combined features from EfficientNetB0 and Xception are processed via fully connected layers and categorized using the Softmax algorithm. The methodology was tested on UCSD and Duke's OCT datasets and produced excellent results. The proposed SE-Improved Hybrid Model outperformed the current best-known approaches, with accuracy rates of 99.58% on the UCSD dataset and 99.18% on the Duke dataset.

conclusionThese findings emphasize the model's ability to effectively diagnose retinal disorders using OCT images and indicate substantial promise for the development of computer-aided diagnostic tools in the field of ophthalmology.

Indexed as

Retinal DiseasesTomography, Optical CoherenceAlgorithmsChoroidal NeovascularizationDeep LearningDiabetic RetinopathyHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedMacular EdemaRetina

Identifiers

PMID39919140
PMCPMC11805419

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.