Evidence map›Paper›PMID 39918987›Full record

ArticleMicrobiology (Reading, England)2025

Crosstalk between cyclic-di-guanosine monophosphate and the sensor kinase MtrB regulates MtrA-dependent genes, bacterial growth, biofilm formation and lysosomal trafficking of

Shreya Bagchi, Arun Kumar Sharma, Soumya Mal, Manikuntala Kundu, Joyoti Basu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology (Reading, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shreya BagchiDepartment of Chemical Sciences, Bose Institute, 93/1 APC Road, Kolkata 700009, India.
Arun Kumar SharmaDepartment of Chemical Sciences, Bose Institute, 93/1 APC Road, Kolkata 700009, India.
Soumya MalDepartment of Biological Sciences, Bose Institute, Unified Academic Campus, EN 80, Sector V, Bidhan Nagar, Kolkata 700091, India.
Manikuntala KunduDepartment of Chemical Sciences, Bose Institute, 93/1 APC Road, Kolkata 700009, India.
Joyoti BasuDepartment of Chemical Sciences, Bose Institute, 93/1 APC Road, Kolkata 700009, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cyclic-di-guanosine monophosphate (c-di-GMP) plays an important role in bacterial signalling networks. C-di-GMP exerts a regulatory function through binding to diverse molecules that include transcription factors, riboswitches and sensor kinases (SKs), thereby regulating diverse processes. Here, we demonstrate the crosstalk between c-di-GMP and the SK MtrB of

Indexed as

Bacterial ProteinsBiofilmsCyclic GMPLysosomesMycobacterium tuberculosisProtein KinasesATP-Binding Cassette TransportersGene Expression Regulation, BacterialHumansMacrophagesPhosphorylationRNA-Binding ProteinsSignal TransductionTranscription FactorsATP-Binding Cassette TransportersBacterial Proteinsbis(3',5')-cyclic diguanylic acidCyclic GMPMtrA protein, BacteriaMtrB protein, BacteriaProtein KinasesRNA-Binding ProteinsTranscription Factorsbiofilmc-di-GMPlysosomal trafficking in macrophagesMycobacterium tuberculosissensor kinase MtrB

Identifiers

PMID39918987
PMCPMC12282275

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.