Evidence map›Paper›PMID 39918861›Full record

ArticleJMIR formative research2025

Women Empowered to Connect With Addiction Resources and Engage in Evidence-Based Treatment (WE-CARE)-an mHealth Application for the Universal Screening of Alcohol, Substance Use, Depression, and Anxiety: Usability and Feasibility Study.

Krystyna Isaacs, Autumn Shifflett, Kajal Patel, Lacey Karpisek, Yi Cui, Maayan Lawental, Golfo Tzilos Wernette, Brian Borsari, Katie Chang, Tony Ma

Abstract read
In one paragraph

Article in JMIR formative research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Krystyna IsaacsBenten Technologies, Manassas, VA, United States.ORCID 0000-0003-4840-4656
Autumn ShifflettBenten Technologies, Manassas, VA, United States.ORCID 0009-0005-2928-6019
Kajal PatelBenten Technologies, Manassas, VA, United States.ORCID 0009-0001-2417-3761
Lacey KarpisekCollege of Behavior and Community Sciences, School of Social Work, University of South Florida, Tampa, FL, United States.ORCID 0000-0002-9826-0008
Yi CuiBenten Technologies, Manassas, VA, United States.ORCID 0009-0005-5908-9809
Maayan LawentalCollege of Behavior and Community Sciences, School of Social Work, University of South Florida, Tampa, FL, United States.ORCID 0000-0001-5139-8205
Golfo Tzilos WernetteUniversity of Michigan, Department of Family Medicine, Ann Arbor, MI, United States.ORCID 0000-0001-7658-1719
Brian BorsariCenter for Data to Discovery and Delivery Innovation, San Francisco Veterans Affairs Health Care System, San Francisco, CA, United States.ORCID 0000-0002-1491-7771
Katie ChangBenten Technologies, Manassas, VA, United States.ORCID 0000-0002-7948-4065
Tony MaBenten Technologies, Manassas, VA, United States.ORCID 0000-0003-3092-0572

Funding

WE-CARE - an innovative platform ofWomen Engaged in Comprehensive Addiction and Recovery Environments for SubstanceUse WomenR43AA029646 · NIAAA · BENTEN TECHNOLOGIES, INC. · PI MA, TONY XUYEN · 2021 to 2021
$332k
NIAAA NIH HHS R43 AA029646
6 · The paper itself

Abstract

backgroundWomen of childbearing age (aged 18-44 years) face multiple barriers to receiving screening and treatment for unhealthy alcohol and substance use, depression, and anxiety, including lack of screening in the primary care setting and lack of support in accessing care. The Women Empowered to Connect with Addiction Resources and Engage in Evidence-based Treatment (WE-CARE) mobile app was developed to test universal screening with women of childbearing age and linkage to care after an anonymous assessment.

objectiveIn this study, we aimed to investigate the feasibility and acceptability of providing anonymous screening instruments through mobile phones for alcohol and substance use, as well as depression and anxiety, for women of childbearing age.

methodsWe used agile development principles based on previous formative research to test WE-CARE mobile health app with women of childbearing age (N=30) who resided in 1 of 6 counties in central Florida. WE-CARE included screening instruments (for alcohol, substance use, depression, and anxiety), a moderated discussion forum, educational microlearning videos, a frequently asked questions section, and resources for linkage to treatment. Individuals were recruited using flyers, academic listserves, and a commercial human subject recruiting company (Prolific). Upon completion of the screening instruments, women explored the educational and linkage to care features of the app and filled out a System Usability Scale to evaluate the mobile health app's usability and acceptability. Postpilot semistructured interviews (n=4) were conducted to further explore the women's reactions to the app.

resultsA total of 77 women downloaded the application and 30 completed testing. Women of childbearing age gave the WE-CARE app an excellent System Usability Scale score of 86.7 (SD 12.43). Our results indicate elevated risk for substance use in 18 of the 30 (60%) participants, 9/18 (50%) also had an elevated risk for anxiety or depression, and 11/18 (61%) had an elevated risk for substance use, anxiety, or depression. Participants reported that WE-CARE was easy to navigate and use but they would have liked to see more screening questions and more educational content. Linkage to care was an issue; however, as none of the women identified as "at-risk" for substance use disorders contacted the free treatment clinic for further evaluation.

conclusionsThe mobile health app was highly rated for acceptability and usability, but participants were not receptive to seeking help at a treatment center after only a few brief encounters with the app. The linkage to care design features was likely insufficient to encourage them to seek treatment. The next version of WE-CARE will include normative scores for participants to self-evaluate their screening status compared with their age- and gender-matched peers and enhanced linkages to care features. Future development will focus on enhancing engagement to improve change behaviors and assess readiness for change.

Indexed as

AnxietyDepressionMass ScreeningMobile ApplicationsSubstance-Related DisordersAdolescentAdultAlcoholismFeasibility StudiesFemaleHumansPatient Acceptance of Health CareTelemedicineYoung Adultalcoholalcohol use disorderanxietyappchatbotchildbearing womendepressiondigital healtheducationempowermente-screeningevidence-based treatmentfeasibilitymental healthmhealthmobile healthscreeningservice linkagesubstance usesubstance use disorderSUDusabilitywomen

Identifiers

PMID39918861
PMCPMC11845888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.