ArticleJapanese journal of ophthalmology2025
Reliability and validity of pre- and post-operative health-related quality of life in strabismus patients using the Japanese version of the adult strabismus questionnaire (AS-20).
Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Responsiveness and minimal important change of the Dutch Adult Strabismus-20 Questionnaire (Dutch-AS-20).Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026Article
- Surgical Approaches for Residual Secondary Gaze Diplopia After Strabismus Surgery: A Case Series.Cureus · 2025Article
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7 authors.
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Abstract
purposeThis study aimed to translate the Adult Strabismus-20 (AS-20) questionnaire into Japanese, creating the JAS-20, to assess health-related quality of life (HRQOL) in Japanese strabismus patients for the first time. The HRQOL was compared between patients with strabismus and those with non-strabismus mild eye diseases to evaluate HRQOL changes pre- and post-strabismus surgery. STUDY
designProspective cohort study.
methodsThe AS-20 was translated into Japanese according to international standards by bilingual health professionals. Participants were recruited from an ophthalmology hospital near Tokyo between May 2022 and August 2023. They included adults over 18 years with strabismus (strabismus group) and those with mild eye diseases without strabismus (control group). Patients with strabismus undergoing surgery were reassessed using the JAS-20 two months after operation. Analyses included comparisons between strabismus and control groups, the presence of diplopia within the strabismus group, and pre- versus post-surgery evaluations.
resultsThe study included 239 patients: 168 in the strabismus group (114 with diplopia and 54 without diplopia) and 71 in the control group. The strabismus group showed significantly lower JAS-20 scores than the control group, indicating a reduced HRQOL. The patients without diplopia scored lower on the psychosocial scale, whereas those with diplopia scored lower on the functional scale. Despite significant post-surgery HRQOL improvements, strabismus patient scores remained below the control group levels.
conclusionsStrabismus affects HRQOL in Japanese patients; it affects functional aspects in patients with diplopia and psychosocial aspects in those without diplopia. Although surgical intervention significantly enhanced HRQOL, it did not equalize with the control group's HRQOL.
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