Evidence map›Paper›PMID 39918697›Full record

ReviewAnalytical sciences : the international journal of the Japan Society for Analytical Chemistry2025

Recent advances in electrochemiluminescence sensing for in vitro cell analysis: a review.

Kosuke Ino, Tomas Mockaitis, Ryota Shikuwa, Kimiharu Oba, Kaoru Hiramoto, Inga Morkvenaite-Vilkonciene, Hiroya Abe, Hitoshi Shiku

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Fluorescence spectroelectrochemistry for the study of electrochemiluminescence of the CdTe quantum dots/tripropylamine coreactant system.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  2. Article
  3. The Fantastic Single-Molecule Techniques.Chemical & biomedical imaging · 2026
    Review
  4. Microphysiological systems for metastasis research: a stepwise approach.Cellular oncology (Dordrecht, Netherlands) · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kosuke InoGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan. kosuke.ino@tohoku.ac.jp.ORCID http://orcid.org/0000-0002-4750-4025
Tomas MockaitisGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Ryota ShikuwaGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Kimiharu ObaGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Kaoru HiramotoFrontier Research Institute for Interdisciplinary Sciences, Tohoku University, Sendai, 980-8577, Japan.ORCID https://orcid.org/0000-0002-2210-7971
Inga Morkvenaite-VilkoncieneLaboratory of Bioelectrochemical Technologies, Department of Nanotechnology, State Research Institute Centre for Physical Sciences and Technology, 10257, Vilnius, Lithuania.
Hiroya AbeGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan.
Hitoshi ShikuGraduate School of Engineering, Tohoku University, Sendai, 980-8579, Japan. hitoshi.shiku.c3@tohoku.ac.jp.

Funding

AMED JP22be1004205AMED JP23be1004205AMED JP24be1004205Japan Society for the Promotion of Science 21H01957Japan Society for the Promotion of Science 22H02102Japan Society for the Promotion of Science 23K17926Japan Society for the Promotion of Science 24H00070
6 · The paper itself

Abstract

Electrochemiluminescence (ECL) is a chemiluminescence phenomenon triggered by electrochemical reactions and is widely used for (bio)chemical analyses and electrochemical bioimaging. Compared to fluorescence sensing, ECL sensing reduces background noise by eliminating autofluorescence associated with excitation light. In addition, compared with conventional electrochemical imaging with scanning electrochemical microscopes, ECL imaging is faster as it requires no scanning. Furthermore, unlike electrode arrays, ECL devices can function without complex wiring, simplifying their construction. These characteristics render ECL sensing a useful analytical tool. Recently, ECL sensing has been widely used for in vitro cell analysis due to high demand for biochips in regenerative medicine, drug screening, and microphysiological systems. This review focuses on recent advancements in ECL-based cell analysis with applications for the detection of H

Indexed as

Biosensing TechniquesElectrochemical TechniquesLuminescent MeasurementsAnimalsHumansHydrogen PeroxideHydrogen PeroxideBipolar electrochemistryCell analysisElectrochemiluminescenceLuminol/H2O2 system[Ru(bpy)3]2+/tri-n-propylamine system

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.