Evidence map›Paper›PMID 39918660›Full record

ArticleOral and maxillofacial surgery2025

Effect of ozone and low power laser as therapeutic alternatives on the alveolar repair process after tooth extraction in rats wistar exposed to nicotine.

Thainy Oliveira Carvalho, Wilson Pereira de Almeida, Fabiano Rodrigues Palma, Paulo Vinícius Fontanella Pilati, Victoria Zanardo, Anna Júlia Leduc Chaves, Sarah Freygang Mendes Pilati

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Article in Oral and maxillofacial surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Thainy Oliveira CarvalhoUniversity of Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil.
Wilson Pereira de AlmeidaUniversity of Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil.
Fabiano Rodrigues PalmaAnaesthesiology and Surgery, Universidade Do Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil.
Paulo Vinícius Fontanella Pilati, R. 119 A, 147 - Centro, Itapema - SC, 88220-000, Brazil.
Victoria ZanardoUniversity of Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil.
Anna Júlia Leduc ChavesUniversity of Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil.
Sarah Freygang Mendes PilatiUniversity of Vale Do Itajaí (UNIVALI), R. Uruguai, 458, C5 - Centro, Itajaí - SC, 88302-901, Brazil. sarahfreygang@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the alveolar repair process in rats exposed to nicotine after tooth extraction, using ozonised water and low-power laser therapy (LPLT) as therapeutic adjuvants. MATERIALS AND

methodsThirty wistar rats (Rattus Norvegicus) were used and given the nicotine solution via subcutaneous tissue. After 7 days, the upper right central incisor was surgically extracted. Three days after the surgical procedure, the animals continued to receive nicotine until the day of euthanasia, totalling 21 days after extraction.

resultsThe result was that the groups that received coadjuvant therapy had neoformed mature bone, unlike the group that did not receive it.

conclusionsBased on the literature and the results obtained, we can conclude that nicotine negatively influenced the healing process and bone repair in the alveoli; however, the use of ozonised water and LPLT, even in the presence of nicotine, was effective, as it enhanced the repair process, making them good options for surgical procedures in patients who smoke.

Indexed as

Alveolar ProcessLow-Level Light TherapyNicotineOzoneTooth ExtractionWound HealingAnimalsMaleRatsRats, WistarNicotineOzoneAlveolar bone repairLaser therapyNicotineOzone therapy

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.