Evidence map›Paper›PMID 39918627›Full record

ArticleFish physiology and biochemistry2025

Effect of dietary supplementation of lauric acid on growth performance, digestive enzymes, serum immune and antioxidant parameters, and intestinal morphology in black sea bream.

Sami Ullah, Fengqin Feng, Minjie Zhao, Jinzhi Zhang, Qingjun Shao

Abstract readRandomized Controlled Trial, Veterinary
PubMed Publisher
In one paragraph

Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sami UllahZhejiang University Zhongyuan Institute, Zhengzhou, 450001, China.
Fengqin FengZhejiang University Zhongyuan Institute, Zhengzhou, 450001, China.
Minjie ZhaoCollege of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China.
Jinzhi ZhangCollege of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. zhangjzs@zju.edu.cn.
Qingjun ShaoCollege of Animal Sciences, Zhejiang University, Hangzhou, 310058, China. qjshao@zju.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An eight-week feeding trial was conducted to examine the impact of dietary supplementation with lauric acid (LA) on juvenile black sea bream. A basal diet was formulated containing 19.9% fish meal, while five additional diets were prepared, each supplemented with varying levels of LA: LA1 (0.01%), LA2 (0.02%), LA3 (0.04%), LA4 (0.08%), and LA5 (0.16%), denoted as LA1 through LA5, respectively. Triplicate tanks were randomly allocated to each diet, each containing 20 fish with an initial weight of 1.55 ± 0.02 g. At the conclusion of the trial, the LA3 group exhibited significantly greater final body weight (FBW), weight gain (WG), specific growth rate (SGR), and protein efficiency ratio (PER) compared to the other groups (P < 0.05), while the feed conversion ratio (FCR) was markedly higher in the control group. No significant differences were detected among the groups in terms of initial body weight (IBW), muscle fiber index (MFI), protein productive value (PPV), condition factor (CF), hepatosomatic index (HSI), intraperitoneal fat (IPF), viscerosomatic index (VSI), and survival rate (SR) (P > 0.05). No significant variations were observed among the groups in the proximate compositions of the dorsal muscle and whole body (p > 0.05). Furthermore, no significant differences were observed in serum immune and antioxidant parameters in the midgut and hindgut and digestive enzyme activity (P > 0.05) among the treatment groups. However, the LA3 group demonstrated significantly higher levels of serum immune response markers IgM, C3, and C4 compared to the other groups, while malondialdehyde (MDA) levels were significantly elevated in the control group relative to the others. The LA3 group demonstrated significantly increased fore-intestinal villus height, crypt depth, villus height-to-crypt depth ratio, and goblet cell count per villus compared to the other groups (P < 0.05).

Indexed as

IntestinesLauric AcidsSea BreamAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsAntioxidantsDietDietary SupplementsAntioxidantslauric acidLauric AcidsAcanthopagrus schlegeliiAntioxidant parametersGrowth performanceIntestinal developmentLauric acid

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.