Evidence map›Paper›PMID 39918620›Full record

ArticleInternational ophthalmology2025

Vitreous hemorrhage in patients with uveitis: a comparative study between adults and children.

Nesrine Abroug, Tarek Dridi, Mootez Mourali, Wijdene Nabi, Imen Ksiaa, Melek Kechida, Sana Khochtali, Bechir Jelliti, Moncef Khairallah

Abstract readComparative Study
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In one paragraph

Article in International ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Nesrine AbrougDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia. nesrineabroug@hotmail.fr.
Tarek DridiDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Mootez MouraliDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Wijdene NabiDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Imen KsiaaDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Melek KechidaDepartment of Internal Medicine, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, Monastir, Tunisia.
Sana KhochtaliDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Bechir JellitiDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.
Moncef KhairallahDepartment of Ophthalmology, Faculty of Medicine, Fattouma Bourguiba University Hospital, University of Monastir, 5000, Monastir, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare clinical findings and visual outcomes of vitreous hemorrhage (VH) associated with uveitis in adults versus children.

methodsA retrospective comparative study.

resultsThere were 36 adults (44 eyes) and 10 children (12 eyes). Median age was 35 years in the adult group and 9.5 years in the pediatric group. VH was the presenting manifestation of the underlying uveitis in 45.7% of patients. VH in the adult group was more frequently associated with vascular sheathing, retinal hemorrhages, and extensive peripheral retinal ischemia on fluorescein angiography (FA), whereas VH in the pediatric group was associated with a significantly lower presenting visual acuity, and more frequently with vitritis and non-occlusive retinal vasculitis with fern-like retinal capillaritis. The most common source of bleeding was ischemia-driven retinal or optic disc neovascularization in the adult group (81.8%, p ≤ 0.001) and inflammation-driven optic disc neovascularization in the pediatric group (66.6%, p ≤ 0.001). A retinal vasoproliferative tumor was the cause of VH in one child (1.8%). Tuberculosis and Behçet's uveitis were the most common etiologies of uveitis in the adult group. Idiopathic intermediate uveitis/pars planitis was the leading cause of VH in the pediatric group. The mean final visual acuity was significantly higher in the pediatric group (20/25) than in the adult group (20/50) (p = 0.045).

conclusionsVH associated with uveitis has a distinctive clinical and etiological profile between adults and children. The main source of bleeding was ischemia-driven neovascularization in adults and inflammation-driven neovascularization in children.

Indexed as

UveitisVisual AcuityVitreous HemorrhageAdolescentAdultChildChild, PreschoolFemaleFluorescein AngiographyFollow-Up StudiesFundus OculiHumansMaleMiddle AgedRetrospective StudiesVitreous BodyOptic disc neovascularizationRetinal neovascularizationRetinal vasculitisUveitisVitreous hemorrhage

Identifiers

PMID39918620

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