Evidence map›Paper›PMID 39918610›Full record

ArticleActa parasitologica2025

Acanthamoeba spp. in Dialysis Water: Assessing the Potential Risk of Transmission to Hemodialysis Patients.

Mona Mohamed Tolba, Heba Elhadad, Shaban Hassan Abu Kabsha, Nesma Seyam El-Kady, Safia Saleh Khalil, Amira Hussein Mohamed, Hend Aly El-Taweel

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Article in Acta parasitologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mona Mohamed TolbaDepartment of Parasitology, Medical Research Institute, Alexandria University, 165 El-Horeya Rd, Al Ibrahimeyah Qebli WA Al Hadrah Bahri, Alexandria, Egypt.
Heba ElhadadDepartment of Parasitology, Medical Research Institute, Alexandria University, 165 El-Horeya Rd, Al Ibrahimeyah Qebli WA Al Hadrah Bahri, Alexandria, Egypt.
Shaban Hassan Abu KabshaBehera Water and Drainage Company, Damanhour, Egypt.
Nesma Seyam El-KadyDepartment of Parasitology, Medical Research Institute, Alexandria University, 165 El-Horeya Rd, Al Ibrahimeyah Qebli WA Al Hadrah Bahri, Alexandria, Egypt.
Safia Saleh KhalilDepartment of Parasitology, Medical Research Institute, Alexandria University, 165 El-Horeya Rd, Al Ibrahimeyah Qebli WA Al Hadrah Bahri, Alexandria, Egypt.
Amira Hussein MohamedDepartment of Experimental and Clinical Internal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Hend Aly El-TaweelDepartment of Parasitology, Medical Research Institute, Alexandria University, 165 El-Horeya Rd, Al Ibrahimeyah Qebli WA Al Hadrah Bahri, Alexandria, Egypt. hend.eltaweel@alexu.edu.eg.ORCID https://orcid.org/0000-0001-5152-2704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcanthamoeba spp. can colonize various freshwater habitats. They are the causative agents of granulomatous amoebic encephalitis and can harbor many microorganisms. We studied the presence of Acanthamoeba spp. in the water system of a hemodialysis unit and assessed the potential for transmission to hemodialysis patients.

methodsWater samples collected from pretreatment and posttreatment water of the treatment station and from input and output water of the dialysis machines were cultured on non-nutrient agar supplemented with Escherichia coli. Blood samples from dialysis patients in the unit and from a control group in the same hospital were tested for anti-Acanthamoeba IgG antibodies.

resultsAcanthamoeba spp. were found in posttreatment water. They were more commonly found in the input water samples (79.2%), than in the output water samples (16.7%) (p = 0.001). Anti-Acanthamoeba IgG antibodies were present in 32.9% of patients and were absent in the control group (p = 0.002). The duration of hemodialysis was significantly longer in seropositive patients than in seronegative patients (p = 0.008).

conclusionThe study highlights the presence of Acanthamoeba spp. in the dialysis system. The relatively high prevalence of anti-Acanthamoeba IgG antibodies and the link between dialysis duration and seropositivity emphasize the importance of rigorous water monitoring.

Indexed as

AcanthamoebaAmebiasisRenal DialysisAdultAgedAntibodies, ProtozoanFemaleHumansImmunoglobulin GMaleMiddle AgedAntibodies, ProtozoanImmunoglobulin GAcanthamoeba spp.Anti-Acanthamoeba IgGDialysisWater

Identifiers

PMID39918610
PMCPMC11805808

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