Evidence map›Paper›PMID 39918607›Full record

ArticleActa parasitologica2025

Larvicidal Efficacies of Nanoliposomes Containing Alpha-pinene, Citral, Camphor, and Thymol Against Aedes aegypti and Anopheles stephensi Mosquito Vectors.

Alireza Sanei-Dehkordi, Narges Fereydouni, Mahmoud Agholi, Seyed AhmadReza Ziaei, Zahra Azadpour, Elham Zarenezhad, Mahmoud Osanloo

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Article in Acta parasitologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Alireza Sanei-DehkordiDepartment of Biology and Control of Disease Vectors, School of Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.ORCID https://orcid.org/0000-0002-4022-0361
Narges FereydouniNoncommunicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-1885-1669
Mahmoud AgholiDepartment of Medical Parasitology and Mycology, School of Medicine, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0002-7443-6507
Seyed AhmadReza ZiaeiStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0009-0003-8144-2467
Zahra AzadpourStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0009-0005-8932-9412
Elham ZarenezhadNoncommunicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran.ORCID https://orcid.org/0000-0003-2805-1910
Mahmoud OsanlooDepartment of Medical Nanotechnology, School of Advanced Technologies in Medicine, Fasa University of Medical Sciences, Fasa, Iran. osanloo_mahmood@yahoo.com.ORCID https://orcid.org/0000-0002-1190-6874

Funding

Fasa University of Medical Sciences 402120
6 · The paper itself

Abstract

backgroundDiseases transmitted by Aedes aegypti or Anopheles stephensi, such as Zika virus, dengue fever, and malaria, pose substantial risks to public health, particularly in tropical areas. Plant-derived compounds have emerged as promising alternatives due to their inherent safety and potential efficiency against mosquitoes. This study aimed to improve the efficacy of certain natural compounds, including α-pinene, citral, camphor, and thymol, by developing nanoliposomal formulations.

methodsThe ‎nanoliposomes containing α-pinene, citral, camphor, and thymol were prepared using the ethanol injection method and then characterized. Using WHO-recommended guidelines, their larvicidal efficacy was investigated against Aedes aegypti and Anopheles stephensi.

resultsThe ‎nanoliposomes particle sizes were 105 ± 7, 86 ± 5, 149 ± 5, and 135 ± 8 nm, and zeta potentials ‎were - 25.1 ± 0.5, -17.2 ± 1.2, -16.4 ± 1.6, and - 21.3 ± 1.7 mV, respectively. In addition, the ATR-FTIR (Attenuated Total Reflectance-Fourier Transform InfraRed) analysis verified the successful loading of the compound. Nanoliposomal compounds exhibited superior performance compared to their non-formulated counterparts in larvicidal bioassays. The nanoliposomes containing thymol showed the highest efficacy, with a Lethal Concentration 50 (LC

conclusionsThe results suggest that nanoliposomes have the potential to serve as an effective vehicle to improve the efficiency of plant-based larvicides. This could play a significant role in developing sustainable mosquito control strategies.

Indexed as

AedesAnophelesInsecticidesLiposomesMosquito VectorsAcyclic MonoterpenesAnimalsBicyclic MonoterpenesLarvaMonoterpenesMosquito ControlNanoparticlesThymolAcyclic Monoterpenesalpha-pineneBicyclic MonoterpenescitralInsecticidesLiposomesMonoterpenesThymolDengue feverLiposomeMalariaNanotechnologyZika virus

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.