Evidence map›Paper›PMID 39918556›Full record

Trial reportExperimental brain research2025

Gamma-frequency transcranial alternating current stimulation over the left posterior parietal cortex enhances the long-term retention of associative memory.

Shunxiang Sun, Hiroki Annaka, Tomonori Nomura

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Experimental brain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Shunxiang SunGraduate School, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, 950-3198, Japan.ORCID http://orcid.org/0009-0001-1134-009X
Hiroki AnnakaFaculty of Rehabilitation, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, 950-3198, Japan.ORCID http://orcid.org/0000-0001-6092-0392
Tomonori NomuraFaculty of Rehabilitation, Niigata University of Health and Welfare, 1398 Shimami-cho, Kita-ku, Niigata, 950-3198, Japan. nomura@nuhw.ac.jp.ORCID http://orcid.org/0000-0001-7446-8886

Funding

Japan Society for the Promotion of Science JP23K10411
6 · The paper itself

Abstract

Transcranial alternating current stimulation (tACS) has been reported to improve associative memory (AM) by modulating the frequency of neural oscillations in the brain; however, whether gamma-frequency (> 30 Hz) tACS in the left posterior parietal lobe (PPC) can enhance memory retention in AM remains unclear. This study aimed to investigate whether memory retention in AM could be improved after gamma-frequency tACS of the left PPC. We used a randomly assigned, double-blind, repeated-measures, sham-control design, in which 28 healthy adult participants were assigned to receive a single 20-min session of gamma-frequency (60 Hz) tACS or sham stimulation. The memory learning task consisted of studying and testing 50 unrelated word pairs three times on day 1. The number of correct responses in the cued recall task was measured at three time points: days 1, 7, and 28. The results revealed a significant difference in the number of correct responses between the interventions on day 7 and day 28. These data suggest that gamma-frequency tACS stimulation of the left PPC enhances the long-term retention of AM in healthy adults.

Indexed as

Association LearningGamma RhythmMemory, Long-TermMental RecallParietal LobeRetention, PsychologyTranscranial Direct Current StimulationAdultDouble-Blind MethodFemaleHumansMaleYoung AdultAssociative memory (AM)Gamma-frequency bandPosterior parietal cortex (PPC)Transcranial alternating current stimulation (tACS)

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.