Evidence map›Paper›PMID 39917991›Full record

ArticleEuropean journal of orthodontics2025

Does incisor inclination change during orthodontic treatment affect gingival thickness and the width of keratinized gingiva? A prospective controlled study.

Dimitrios Kloukos, George Koukos, Ioannis Doulis, Andreas Stavropoulos, Christos Katsaros

Abstract read
In one paragraph

Article in European journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dimitrios KloukosDepartment of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern, Freiburgstrasse 7, CH-3010 Bern, Switzerland.ORCID 0000-0002-0665-238X
George KoukosDepartment of Periodontology, 251 Hellenic Air Force Hospital, Panagioti Kanellopoulou 3, 11525, Athens, Greece.
Ioannis DoulisDepartment of Orthodontics and Dentofacial Orthopedics, 251 Hellenic Air Force Hospital, Panagioti Kanellopoulou 3, 11525, Athens, Greece.
Andreas StavropoulosPeriodontology, Faculty of Odontology, Carl Gustafs väg 34, 21421, Malmö University, Malmö, Sweden.
Christos KatsarosDepartment of Orthodontics and Dentofacial Orthopedics, School of Dental Medicine, University of Bern, Freiburgstrasse 7, CH-3010 Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis prospective controlled study aimed to assess whether changes in mandibular incisor inclination during orthodontic treatment with fixed appliances affect gingival thickness (GT) and the width of keratinized gingiva (WKG), and having as reference an untreated group of participants. MATERIALS AND

methodsForty consecutively recruited adult orthodontic patients and 40 untreated volunteers, matched for age and gender and selected from the same background population serving as controls, were included. Mandibular incisor inclination was measured in lateral cephalograms before treatment commencement (T0) and 1 month before fixed appliances' removal (T1). Gingival thickness was measured using an Ultrasound Device (US) and width of keratinized gingiva (WKG) using a standard periodontal probe within the frames of a full periodontal examination at T0, T1, and 1 year after bracket removal (T2), that is, at about 30 months from T1.

resultsNineteen females and 21 males in each group [mean age in years (range): intervention group 23.1 (16.8-43.3); control: 21.85 (18.2-43.9)] were analysed. Overall, change in incisor proclination [mean change in Incisor Mandibular Angle Plane-IMPA (ΔIMPA) was 6.35° (SD 5.08°)] was not associated with any significant change in soft tissue thickness and with alterations in WKG. The group receiving fixed appliances did not exhibit thickening or thinning of GT in comparison to the control group; the WKG was reduced in the intervention group in comparison to the untreated group, where it essentially remained unchanged (#41: coeff.: -0.29, P value: .1, 95% CIs: -0.65, 0.06; #31: coeff.: -0.51, P value: .01, 95% CIs: -0.88, -0.14).

conclusionsLower incisor proclination during orthodontic treatment does not appear to significantly alter GT and WKG, but orthodontic treatment, overall, leads to reduction of the WKG.

Indexed as

GingivaIncisorAdolescentAdultCase-Control StudiesCephalometryFemaleHumansKeratinsMaleMandibleOrthodontic Appliances, FixedOrthodontic BracketsProspective StudiesTooth Movement TechniquesYoung AdultKeratinsgingival phenotypegingival thicknessincisor proclinationorthodontic tooth movementwidth of keratinized gingiva

Identifiers

PMID39917991
PMCPMC11803420

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.