ArticleCombinatorial chemistry & high throughput screening2026
Isolation, Characterization, and Evaluation of the Mucilage from
Article in Combinatorial chemistry & high throughput screening, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundMany plant-derived compounds have been used as pharmaceutical excipients due to their various functional properties. One such plant product is mucilage, which has created great interest among researchers to be explored for numerous biological applications.
objectivesThe objective of the present study was to isolate mucilage from the leaves of
methodsThe obtained mucilage was screened for its phytochemicals and characterized physiochemically using FTIR, XRD, DSC, and SEM. Its antioxidant property was analyzed using DPPH and FRAP assays. The anticancer activity of the mucilage was evaluated against colon and cervical cancer cell lines using the MTT assay.
resultsThe phytochemical screening of the mucilage showed the presence of reducing sugars, flavonoids, amino acids, tannins, saponins, and steroids. The yield percentage of mucilage was 24%, and it has a swelling index of 10. It was found to be soluble in warm water and showed a pH of 9. The FTIR spectra of mucilage showed characteristic peaks of its functional groups. The SEM image showed a porous and rough morphological surface of mucilage. The obtained mucilage demonstrated antioxidant activity by DPPH and FRAP assays and exhibited anticancer activity against cervical and colon cancer cell lines using the MTT assay.
conclusionMucilage contains many phytochemicals with various functional properties like antioxidant and anti-cancer activities. Thus, the isolated mucilage from Pedalium murex Linn. showed promising characteristics that could be tailor-made for various biological applications.
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