Evidence map›Paper›PMID 39917869›Full record

ArticleDrug testing and analysis2025

Screening and Quantification of the Synthetic Cannabinoid Receptor Agonist 5F-MDMB-PINACA From Seized Prison Paper Using Ultraperformance Liquid Chromatography-Mass Spectrometry Approaches.

Giorgia Vaccaro, Jacqueline L Stair, Stewart B Kirton, Daniel Baker, Amira Guirguis

Abstract readValidation Study
In one paragraph

Article in Drug testing and analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Interpol review of forensic drug chemistry, 2022-2025.Forensic science international. Synergy · 2026
    Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Giorgia VaccaroDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.ORCID https://orcid.org/0000-0002-2895-4952
Jacqueline L StairDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.
Stewart B KirtonDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.
Daniel BakerDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.
Amira GuirguisDepartment of Clinical, Pharmaceutical and Biological Science, School of Life and Medical Sciences, University of Hertfordshire, Hatfield, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infusing synthetic cannabinoid receptor agonists on paper quickly became a main route for illicit entry into prisons (i.e., mail correspondence) in the last decade. So far, there are limited data on validated detection methods and typical concentration profiles of these substances on paper to inform interventions. An approach to quantify and map the synthetic cannabinoid receptor agonist (SCRA) 5F-MDMB-PINACA on a seized paper sample from a UK Prison was determined using ultraperformance liquid chromatography-mass spectrometry. The seized paper sample was initially screened using ultraperformance liquid chromatography-quadrupole time-of-flight-mass spectrometry that confirmed the presence of 5F-MDMB-PINACA. A quantification method was then optimised and validated for the SCRA using a simple liquid chromatography-quadrupole Dalton-mass spectrometry system. Percentage recovery studies were carried out on paper spiked with 1, 5 and 20 mg/cm

Indexed as

Cannabinoid Receptor AgonistsCannabinoidsIllicit DrugsIndolesSubstance Abuse DetectionChromatography, High Pressure LiquidChromatography, LiquidHumansLimit of DetectionLiquid Chromatography-Mass SpectrometryMass SpectrometryPaperPrisonsTandem Mass Spectrometry5F-MDMB-PICACannabinoid Receptor AgonistsCannabinoidsIllicit DrugsIndoles5F‐MDMB‐PINACAHPLC‐MSnew psychoactive substancesprisonsynthetic cannabinoids

Identifiers

PMID39917869
PMCPMC12401647

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.