Evidence map›Paper›PMID 39917848›Full record

ArticleThe Journal of international medical research2025

Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report.

Saja Karaja, Ahmad Almohamed, Ayham Qatza, Ahmed Aldolly, Sanaa Mansour, Alae Aldin Almasri

Abstract readCase Reports
In one paragraph

Article in The Journal of international medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Saja KarajaUniversity of Hama College of Human Medicine, Hama, Syria.ORCID 0009-0009-9640-7406
Ahmad AlmohamedUniversity of Hama College of Human Medicine, Hama, Syria.ORCID 0009-0000-0893-3989
Ayham QatzaUniversity of Hama College of Human Medicine, Hama, Syria.
Ahmed AldollyUniversity of Hama College of Human Medicine, Hama, Syria.ORCID 0009-0005-7034-0988
Sanaa MansourMinistry of Health, Hama National Hospital, Hama, Syria.
Alae Aldin AlmasriMinistry of Health, Hama National Hospital, Hama, Syria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cutaneous metastasis (CM) is a rare phenomenon, occurring in only 0.6% to 10.4% of oncology patients. Breast carcinoma represents nearly one-third of all CM cases, although it manifests in a minority of patients with breast cancer (BC). Notably, CMs are detected at the time of primary tumor diagnosis in 6.3% of patients with BC and serve as the initial clinical presentation in only 3.5% of patients. We present a case involving a 53-year-old woman with a 5-month history of asymptomatic infiltrating nodules in the axillae and trunk. Skin biopsy and immunohistochemical analysis confirmed metastatic breast carcinoma with positive estrogen receptor staining. This case underscores the importance of early detection and precise diagnostic techniques in managing metastatic adenocarcinoma with cutaneous manifestations. Despite the promising outcome of the initial treatment, the disease progression in this case highlights the aggressive nature of CMs and the ongoing need for research and advanced therapeutic strategies.

Indexed as

AdenocarcinomaBreast NeoplasmsCarcinoma, LobularSkin NeoplasmsFemaleHumansMiddle AgedBreast cancercase reportcutaneous metastasishormone receptor-positive breast cancerlobular breast carcinomaskin lesion

Identifiers

PMID39917848
PMCPMC11806458

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.