Evidence map›Paper›PMID 39917761›Full record

ArticleNeuro-oncology practice2025

Improvements in pain interference among geographically diverse adults with neurofibromatosis: Results from a fully powered randomized controlled trial.

Julia E Hooker, James D Doorley, Jonathan Greenberg, Jafar Bakhshaie, Heena R Manglani, Ellie A Briskin, Ana-Maria Vranceanu

Registry-linked trialAbstract read
In one paragraph

Article in Neuro-oncology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03406208 (Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03406208 nacompletednot on this map

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

TypeinterventionalSponsorMassachusetts General HospitalRan2017 to 2022Enrolled228ConditionsNeurofibromatoses, Neurofibromatosis 1, Neurofibromatosis 2, SchwannomatosisArmsStress and Symptom Management Program 1, Stress and Symptom Management Program 2
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Julia E HookerDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-9890-7572
James D DoorleyDepartment of Sports Medicine, United States Olympic & Paralympic Committee, Colorado Springs, Colorado, USA.ORCID https://orcid.org/0000-0001-9080-4915
Jonathan GreenbergDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-4875-2207
Jafar BakhshaieDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-5906-1292
Heena R ManglaniDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8078-6389
Ellie A BriskinDepartment of Psychiatry, Weill Cornell Institute of Geriatric Psychiatry, Weill Cornell Medicine, New York, New York, USA.
Ana-Maria VranceanuDepartment of Psychiatry, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-3994-6488

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pain is prevalent among adults with neurofibromatoses (NF) and hinders quality of life. Pain management for NF is predominantly pharmacological and often ineffective. Psychosocial treatments improve pain outcomes in other chronic illness populations but have not been developed and tested in fully powered efficacy trials among adults with NF. Using data from a fully powered randomized clinical trial of an 8-week mind-body program (Relaxation Response Resiliency Program for NF [3RP-NF]) versus a health education control (HEP-NF), we examined (1) improvements in pain intensity and pain interference, and (2) mechanisms underlying improvements. Methods: Participants ( Results: There was a statistically significant change in pain interference over time Conclusions: Participation in the 3RP-NF is associated with sustained improvement in pain interference. Improvement occurred through increased coping. Trial Registration: ClinicalTrials.gov Identifier: NCT03406208. Trial Registration URL: https://clinicaltrials.gov/study/NCT03406208.

Indexed as

copingmindfulnessneurofibromatosispainsocial support

Identifiers

PMID39917761
PMCPMC11798604

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.