Evidence map›Paper›PMID 39917749›Full record

ArticleNeuro-oncology practice2025

Financial toxicity of oral chemotherapy in patients with primary brain tumors.

Mallika P Patel, Mary Lou Affronti, Evan D Buckley, James E Herndon Ii, Emma M Mackowsky, Margaret O Johnson, Katherine B Peters

Abstract read
In one paragraph

Article in Neuro-oncology practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Exploring the Impact of Financial Toxicity in COPD: A Qualitative Study.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2026
    Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mallika P PatelThe Preston Robert Tisch Brain Tumor Center, Duke University Medical Center, Durham, North Carolina, USA.
Mary Lou AffrontiDuke School of Nursing, Duke University, Durham, North Carolina, USA.
Evan D BuckleyDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, USA.
James E Herndon IiDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, USA.
Emma M MackowskyDepartment of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.
Margaret O JohnsonDepartment of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.
Katherine B PetersDepartment of Neurosurgery, Duke University Medical Center, Durham, North Carolina, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cancer treatment costs continue to rise with the development of new agents. Financial toxicity is defined as the quantifiable costs associated with cancer and cancer treatment in addition to the patient's associated distress. This study's rationale is to better understand the financial burden of oral chemotherapies from the perspective of patients with primary brain tumors. Methods: After one cycle of oral chemotherapy, we requested patients to complete the financial toxicity-functional assessment of chronic illness therapy (COST-FACIT) survey and additional questions relevant to insurance and cost. We summarized responses with descriptive statistics within strata defined by on-label or off-label oral therapy. Results: Sixty surveys were completed, with most patients ( Conclusions: Discussing medication costs with patients is an essential part of chemotherapy initiation and may mitigate undue psychosocial and financial distress.

Indexed as

brain tumorfinancial toxicitygliomaoral chemotherapyquality of life

Identifiers

PMID39917749
PMCPMC11798601

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.