ArticleEuropean journal of anaesthesiology and intensive care2024
Intraoperative hypotension and its association with acute kidney injury in patients undergoing elective cardiac surgery: a large retrospective cohort study.
Article in European journal of anaesthesiology and intensive care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Cardiac Surgery-Associated Acute Kidney Injury: Procedure-Specific Incidence and Impact on Mortality-An Algorithm-Based Big Data Fusion Analysis.Medical sciences (Basel, Switzerland) · 2026Article
- Intraoperative renal and cerebral tissue oxygen saturation measurements to predict postoperative acute kidney injury in pediatric cardiac surgery: a prospective observational study.Journal of clinical monitoring and computing · 2026Observational
- Preoperative malnutrition is a risk factor for intraoperative hypotension in high-risk surgical patients: a propensity score-matched cohort study.Perioperative medicine (London, England) · 2025Article
- Soluble Urokinase Plasminogen Activator Receptor (suPAR) Plasma Concentration Is Reduced Using Minimized Extracorporeal Circulation: Results of a Secondary Analysis of a Prospective Observational Study.Journal of clinical medicine · 2025Article
- Risk factors and prognosis of post-surgical acute kidney injury in elderly patients based on the MIMIC-IV database.European journal of medical research · 2025Review
- Intraoperative hypotension trajectories and their predictive value for major postoperative complications: a retrospective cohort study.Frontiers in medicine · 2025Article
- The hidden cost of hypotension: redefining hemodynamic management to improve patient outcomes.Brazilian journal of anesthesiology (Elsevier)Article
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6 authors.
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Abstract
backgroundIntraoperative hypotension (IOH) is known to affect renal outcomes in noncardiac surgery. However, it is unclear whether intraoperative hypotension (IOH) causes postoperative acute kidney injury following cardiac surgery.
objectiveThis study aimed to determine whether the duration of IOH during cardiac surgery is associated with the incidence of postoperative acute kidney injury (AKI) and identify its impact on long-term outcomes.
designRetrospective cohort study.
settingAcademic university hospital (Heart and Diabetes Center, Bad Oeynhausen, Germany). PATIENTS: A cohort of 28 909 patients who underwent elective cardiac surgery between 1 January 2009 and 31 December 2018.
interventionsIOH was defined as intraoperative mean arterial blood pressure (MAP) of less than 60 mmHg for more than 2 min. The cumulative duration of these IOH events was recorded each patient.
main outcome measuresThe primary outcome was the incidence of AKI according to the KDIGO criteria (Kidney Disease: Improving Global Outcomes). Logistic regression analysis was used to analyse the associations between IOH and the incidence of AKI. Secondary outcomes were the independent predictors for the incidence of AKI.
resultsPostoperative AKI was observed in 42.9% of patients. The cumulative duration of IOH (minutes) had a significant influence on the incidence of AKI [odds ratio (OR) 1.004; 95% confidence interval (CI) 1.003 to 1.005;
conclusionsThe cumulative duration of IOH is an independent risk factor for the occurrence of postoperative AKI after cardiac surgery.
trial registrationEthics Committee of the Ruhr University Bochum (Register number 2019-491).
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