Evidence map›Paper›PMID 39917596›Full record

ArticleHealth science reports2025

First-Line Levofloxacin-Based Triple Therapy Versus Standard Bismuth-Based Quadruple Therapy for

Abdulrhman Khaled Al Abdulqader, Turki Abdullah Alamri, Mahdi Abdullah Alhamad, Somaia Shehab El-Deen, Abdallah Essa, Raed Abdullah Alfayez, Baqer Mohammed Albaqshi, Adnan Salah Almajed, Mohammed Yousef Alhassan, Ali Essa and 6 more

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Eradication rates of Helicobacter pylori regimens and predictors of treatment failure: A multicenter real-world study in Saudi Arabia.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026
    Article
  3. Therapeutic advances and future directions inFrontiers in microbiology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Abdulrhman Khaled Al AbdulqaderInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.ORCID 0009-0008-0435-8081
Turki Abdullah AlamriInternal Medicine Department, Gastroenterology Unit King Fahad University Hospital Al Khobar Kingdom of Saudi Arabia.
Mahdi Abdullah AlhamadKing Fahad Specialist Hospital Dammam Kingdom of Saudi Arabia.
Somaia Shehab El-DeenInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.ORCID 0000-0003-1429-0363
Abdallah EssaInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.ORCID 0000-0001-6542-8532
Raed Abdullah AlfayezKing Fahad Medical City Riyadh Kingdom of Saudi Arabia.
Baqer Mohammed AlbaqshiKing Saud Medical City Riyadh Kingdom of Saudi Arabia.
Adnan Salah AlmajedCollege of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.
Mohammed Yousef AlhassanCollege of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.
Ali EssaFaculty of Medicine, Menoufia University Shebin El-Kom Egypt.ORCID 0009-0003-8211-0632
Ahmed Abdullah AlbadraniInternal Medicine Department College of Medicine, Prince Sattam Bin Abdulaziz University Al-Kharj Kingdom of Saudi Arabia.
Omar AlomairInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.ORCID https://orcid.org/0000-0002-8498-1621
Bashaeer Abdullh Al JalalInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.
Mohammed Yousef AlmulhimInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.ORCID 0009-0001-6347-4743
Abdullah AlotaibiInternal Medicine Department, Gastroenterology Unit King Fahad University Hospital Al Khobar Kingdom of Saudi Arabia.
Ehab DarwishInternal Medicine Department College of Medicine, King Faisal University Al-Ahsa Kingdom of Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Antibiotic resistance in Saudi Arabia has led to decreased efficacy of conventional triple therapy for Methods: This retrospective analysis included 197 treatment-naïve adults with Results: There were no differences between groups in terms of age, sex, nationality, or type of proton pump inhibitor (PPI) used. The bismuth-based quadruple therapy group exhibited a markedly superior success rate compared to the levofloxacin-based triple therapy group when the latter was administered for 7 or 10 days (81.03% vs. 6.66%, Conclusion: Quadruple treatment based on bismuth is superior to triple therapy based on levofloxacin for eradicating

Indexed as

bismuthefficacyeradicationH. pylorilevofloxacin

Identifiers

PMID39917596
PMCPMC11798733

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.