Evidence map›Paper›PMID 39917420›Full record

ArticleJournal of clinical and experimental hepatology

Drug-induced Autoimmune-like Hepatitis With Pathological Features of Giant Cell Hepatitis.

Jie Yao, Yongqin Yan, Mei Ruan, Haiyan Lin, Dongliang Li, Zhiyu Zeng

Abstract read
In one paragraph

Article in Journal of clinical and experimental hepatology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Study of serum tumor markers in the early diagnosis of pancreatic cancer.World journal of gastrointestinal oncology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jie YaoDepartment of Hepatobiliary Disease, Fuzhou General Clinical Medical College of Fujian Medical University, The 900th Hospital of Joint Logistics Support Force, No. 156 West Second Ring North Road, Gulou District, Fuzhou, Fujian, 350025, China.
Yongqin YanDepartment of Pathology, The 900th Hospital of Joint Logistics Support Force, No. 156 West Second Ring North Road, Gulou District, Fuzhou, Fujian, 350025, China.
Mei RuanDepartment of Hepatobiliary Disease, The Third People's Hospital of Fujian University of Traditional Chinese Medicine, No. 363 Guobin Avenue, Minhou Street, Fuzhou, Fujian, 350100, China.
Haiyan LinDepartment of Hepatobiliary Disease, The 900th Hospital of Joint Logistics Support Force, No. 156 West Second Ring North Road, Gulou District, Fuzhou, Fujian, 350025, China.
Dongliang LiDepartment of Hepatobiliary Disease, Fuzhou General Clinical Medical College of Fujian Medical University, The 900th Hospital of Joint Logistics Support Force, No. 156 West Second Ring North Road, Gulou District, Fuzhou, Fujian, 350025, China.
Zhiyu ZengDepartment of Hepatobiliary Disease, The 900th Hospital of Joint Logistics Support Force, No. 156 West Second Ring North Road, Gulou District, Fuzhou, Fujian, 350025, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and methods: The differentiation between drug-induced autoimmune-like hepatitis (DI-ALH) and autoimmune hepatitis (AIH) can be confusing and challenging. We present a case of DI-ALH characterized by positive autoantibodies, elevated immunoglobulin G (IgG) levels and histology characteristics of giant cell hepatitis. Results: A liver biopsy was performed for etiology clarification, DI-ALH was diagnosed. Following treatment with corticosteroids and azathioprine, the patient's liver function remained normal without recurrence. Conclusions: Distinguishing DI-ALH from AIH based on the possibility of discontinuing immunosuppression and the histological features. Clinicians need to investigate patient's medical history, serological tests, and pathological changes to establish a correct diagnosis.

Indexed as

autoimmune hepatitisDrug-induced autoimmune-like hepatitisgiant cell hepatitis

Identifiers

PMID39917420
PMCPMC11795586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.