Evidence map›Paper›PMID 39917404›Full record

ArticleTurkish journal of surgery2024

Surgical and survival outcomes of cytoreductive surgery alone or with perioperative intraperitoneal chemotherapy in high peritoneal cancer index.

Metin Ercan, Mehmet Aziret, Kerem Karaman, Osman Köse, Volkan Öter, Hakan Yırgın, Ahmet Kaya, Yavuz Selim Kahraman, Elif Köse, Erdal Birol Bostancı and 1 more

Abstract read
In one paragraph

Article in Turkish journal of surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Metin ErcanDepartment of Surgical Oncology, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0001-8294-0239
Mehmet AziretDepartment of Gastroenterological Surgery, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0001-6758-7289
Kerem KaramanDepartment of Gastroenterological Surgery, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0003-0143-9712
Osman KöseDepartment of Gynecological Oncology Surgery, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0001-5656-6853
Volkan ÖterClinic of Gastroenterological Surgery, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye.ORCID 0000-0002-0639-1917
Hakan YırgınDepartment of Gastroenterological Surgery, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0001-7253-0041
Ahmet KayaDepartment of Surgical Oncology, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0002-9635-4940
Yavuz Selim KahramanDepartment of Surgical Oncology, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0001-6639-9593
Elif KöseDepartment of Public Health, Sakarya University Faculty of Medicine, Sakarya, Türkiye.ORCID 0000-0002-2232-4538
Erdal Birol BostancıClinic of Gastroenterological Surgery, University of Health Sciences, Ankara City Hospital, Ankara, Türkiye.ORCID 0000-0002-0663-0156
Orhan ÜnalDepartment of Gynecological Oncology Surgery, Yeditepe University Faculty of Medicine, İstanbul, Türkiye.ORCID 0000-0002-2525-2461

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: The aim of this study was to examine the early surgical and long-term survival outcomes of cytoreductive surgery (CRS) alone and CRS plus perioperative intraperitoneal chemotherapy (IPC) in patients with peritoneal metastases (PM). Material and Methods: CRS alone or CRS plus IPC was performed on 122 patients for various intraabdominal PMs. Patients were divided into two groups as PCI ≤19 and PCI >19 to compare early surgical outcomes. Results: Among PM patients 70 (57.4%) were of non-ovarian and 52 (42.6%) were of ovarian origin. Of the patients 74 (60.7%) were in the peritoneal cancer index (PCI) ≤19 group and 48 (39.3%) were in the PCI >19 group. The complication ratio of PCI >19 group was higher than that of the PCI ≤19 group and median overall survival (OS) of PCI >19 group was lower than that of the PCI ≤19 group. Complete or nearly complete (CCR-0/CCR-1) resections rates were similar in both groups (95.9% in the PCI ≤19 group and 93.8% in the PCI >19 group). However, CCR-0 resection rate was found to be lower in the PCI >19 group compared to the PCI ≤19 group (60.8% vs. 39.6%) (p <0.001). Conclusion: CCR-0/CCR-1 resections can be achieved with CRS in most patients with PCI >19 score. It would be appropriate to consider CRS or CRS plus perioperative IPC for palliative purposes in selected patients with PCI >19 score.

Indexed as

cytoreductive surgeryearly post-operative intraperitoneal chemotherapyhyperthermic intraperitoneal chemotherapyperitoneal cancer indexPeritoneal metastases

Identifiers

PMID39917404
PMCPMC11792903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.