Evidence map›Paper›PMID 39917375›Full record

ArticleClinical case reports2025

Deep Brain Stimulation in the Bed Nucleus of Stria Terminalis and Medial Forebrain Bundle in Two Patients With Treatment-Resistant Depression and Generalized Anxiety Disorder-A Long-Term Follow-Up.

Matilda Naesström, Patric Blomstedt, Viktoria Johansson

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Matilda NaesströmDepartment of Clinical Sciences, Psychiatry Umeå University Umeå Sweden.ORCID https://orcid.org/0000-0001-9679-1609
Patric BlomstedtDepartment of Clinical Sciences, Neurosciences Umeå University Umeå Sweden.
Viktoria JohanssonDepartment of Clinical Sciences, Psychiatry Umeå University Umeå Sweden.ORCID https://orcid.org/0000-0003-3775-7245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report presents positive outcomes from deep brain stimulation (DBS) targeting the bed nucleus of the stria terminalis (BNST) in two patients with treatment-resistant depression and generalized anxiety disorder. DBS effects in the medial forebrain bundle (MFB) area were unclear. Further research into DBS's efficacy when comorbid anxiety is present is required.

Indexed as

bed nucleus of the stria terminalisclinical trialdeep brain stimulationdepressiongeneralized anxiety disordermedial forebrain bundle

Identifiers

PMID39917375
PMCPMC11798865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.