Evidence map›Paper›PMID 39917298›Full record

ArticleFrontiers in immunology2025

The autoimmune disease risk variant NCF1-His90 is associated with a reduced risk of tuberculosis in women.

Xinjun Hu, Shasha Li, Renliang Huang, Ziwei Fu, Chenyu Ma, Zheng Cheng, Hongjun Hu, Qiaomiao Zhou, Frank Petersen, Xinhua Yu and 1 more

Abstract read
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In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xinjun Hu *Department of Infectious Diseases, The First Affiliated Hospital of Henan University of Science and Technology, Henan Medical Key Laboratory of Gastrointestinal Microecology and Hepatology, Luoyang, China.
Shasha Li *Institute of Psychiatry and Neuroscience, Xinxiang Medical University, Xinxiang, China.
Renliang Huang *Department of Genetics and Prenatal Diagnosis, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Ziwei FuInstitute of Psychiatry and Neuroscience, Xinxiang Medical University, Xinxiang, China.
Chenyu MaDepartment of Infectious Diseases, The First Affiliated Hospital of Henan University of Science and Technology, Henan Medical Key Laboratory of Gastrointestinal Microecology and Hepatology, Luoyang, China.
Zheng ChengInstitute of Psychiatry and Neuroscience, Xinxiang Medical University, Xinxiang, China.
Hongjun HuDepartment of Surgical Oncology, Xinxiang Central Hospital, The Fourth Clinical of Xinxiang Medical University, Xinxiang, China.
Qiaomiao ZhouDepartment of Genetics and Prenatal Diagnosis, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Frank PetersenPriority Area Chronic Lung Diseases, Research Center Borstel - Leibniz Lung Center, Members of the German Center for Lung Research (DZL), Borstel, Germany.
Xinhua YuDepartment of Genetics and Prenatal Diagnosis, Hainan Women and Children's Medical Center, Haikou, Hainan, China.
Junfeng ZhengInstitute of Psychiatry and Neuroscience, Xinxiang Medical University, Xinxiang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The neutrophil cytosolic factor 1 ( Methods: To test this hypothesis, we investigated whether the Results: Our results showed that the Conclusion: This study demonstrates that the autoimmune disease-causal NCF1 variant is associated with a protective effect against TB infection.

Indexed as

Autoimmune DiseasesGenetic Predisposition to DiseaseNADPH OxidasesPolymorphism, Single NucleotideTuberculosisAdultAgedCase-Control StudiesFemaleGenotypeHumansMaleMiddle AgedRisk FactorsSex FactorsNADPH Oxidasesneutrophil cytosolic factor 1autoimmune diseases (AD)evolutionary trade-offsgenetic associationinfectious diseasesneutrophil cytosolic factor 1 (NCF1)tuberculosis

Identifiers

PMID39917298
PMCPMC11799249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.