Evidence map›Paper›PMID 39917223›Full record

ArticleBioinformation2024

Validation of endothelin-1 and interleukin-1β as a biomarker for diagnosing peri-implant disorders.

Pranav V Manek, Arpita Srivastava, Rahul Shrivastava, Miloni Bhatt, Naina Pattnaik, Manish Kumar

Abstract read
In one paragraph

Article in Bioinformation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pranav V ManekDepartment of Oral Medicine and Radiology, Pacific Dental College and Research Centre, Udaipur, Rajasthan, India.
Arpita SrivastavaDepartment of Oral Medicine and Radiology, Government College of Dentistry Indore, M.P, India.
Rahul ShrivastavaPrivate Practitioner, Department of Prosthodontics, Revti Dental Clinic, Indore, MP, India.
Miloni BhattDepartment of Prosthodontics, Karnavati school of dentistry, Karnavati University, Gujarat, India.
Naina PattnaikDepartment of Periodontics and Oral Implantology, Kalinga Institute of Dental Science, KIIT Deemed to be University Patia, Bhubaneswar, Odisha, India.
Manish KumarDepartment of Dentistry, Dr. Laxminarayan Pandey Government Medical College & Hospital, Ratlam, M.P, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endothelin-1 (ET-1) and interleukin-1β (IL-1β) is increased in periodontitis and is linked to inflammatory cytokines among other variables. The purpose of this study was to ascertain if ET-1 and IL-1β are utilized as an early indicator for peri-implant mucositis (PM) and peri-implantitis (PI), as well as to look into the relationship between ET-1 and IL-1β levels and peri-implant illnesses. 58 patients (30 males and 28 females) with a total of 152 implants were included for final analyses. Three groups were formed from the 152 qualifying implants. A plastic probe was used at low pressure of 0.25N to assess the peri-implant parameters like probing pocket depth (PPD), modified gingival index (mGI), BOP being present or absent and modified plaque index (mPI). Mean bone loss (MBL) and the average annual bone loss (ABL) were evaluated. The values were significantly greater in PI group and PM group as compared to healthy subjects. ET-1 and IL-1β levels are significantly increased in peri-implant illnesses. ET-1 and IL-1β may be utilized as diagnostic indicator for peri-implant disorders.

Indexed as

biomarkerEndothelin-1peri-implantitisperi-implant mucositis

Identifiers

PMID39917223
PMCPMC11795484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.